Psmd12 proteasome 26S subunit, non-ATPase 12 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Psmd12provided by RGD
Full Name: proteasome 26S subunit, non-ATPase 12provided by RGD
Primary source: RGD:1359305
See related: Ensembl:ENSRNOG00000003117 AllianceGenome:RGD:1359305
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of nuclear proteasome complex and proteasome regulatory particle, lid subcomplex. Predicted to be active in cytoplasm. Orthologous to human PSMD12 (proteasome 26S subunit, non-ATPase 12). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Muscle (RPKM 474.5), Heart (RPKM 390.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q32.1

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (92937957..92956601)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (92438223..92457323)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (95706808..95725452)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome accessory complex	ISO Inferred from Sequence Orthology more info
part_of proteasome complex	ISO Inferred from Sequence Orthology more info
part_of proteasome regulatory particle	ISO Inferred from Sequence Orthology more info
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 12

Names: 26S proteasome non-ATPase regulatory subunit 12-like; proteasome (prosome, macropain) 26S subunit, non-ATPase, 12; proteasome 26S non-ATPase subunit 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005875.1 → NP_001005875.1 26S proteasome non-ATPase regulatory subunit 12

See identical proteins and their annotated locations for NP_001005875.1

Status: PROVISIONAL

Source sequence(s)

BC083758

UniProtKB/TrEMBL

A0A8I6AAD5, Q5XIC6

Related

ENSRNOP00000004283.2, ENSRNOT00000004283.5

Conserved Domains (1) summary

COG5071
Location:14 → 456

RPN5; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]