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Actg1 actin, gamma 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287876, updated on 25-Nov-2021

Summary

Official Symbol
Actg1provided by RGD
Official Full Name
actin, gamma 1provided by RGD
Primary source
RGD:1304556
See related
EnsemblRapid:ENSRNOG00000036701
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Actg
Expression
Biased expression in Spleen (RPKM 4452.9), Kidney (RPKM 4243.0) and 9 other tissues See more
Orthologs
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Genomic context

See Actg1 in Genome Data Viewer
Location:
10q32.3
Exon count:
7
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (105619738..105622587, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (109518429..109521288, complement)

Chromosome 10 - NC_051345.1Genomic Context describing neighboring genes Neighboring gene BAH domain and coiled-coil containing 1 Neighboring gene uncharacterized LOC120095309 Neighboring gene uncharacterized LOC102546528 Neighboring gene uncharacterized LOC120095311 Neighboring gene uncharacterized LOC120095310 Neighboring gene fascin actin-bundling protein 2, retinal

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables profilin binding ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of postsynaptic actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables structural constituent of postsynaptic actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within_positive_effect angiogenesis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cellular response to interferon-gamma ISO
Inferred from Sequence Orthology
more info
 
involved_in morphogenesis of a polarized epithelium ISO
Inferred from Sequence Orthology
more info
 
involved_in platelet aggregation ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of wound healing ISO
Inferred from Sequence Orthology
more info
 
involved_in postsynaptic actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
involved_in protein localization to bicellular tight junction ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of focal adhesion assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of transepithelial transport ISO
Inferred from Sequence Orthology
more info
 
involved_in response to calcium ion IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to mechanical stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in retina homeostasis ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of_or_within sarcomere organization ISO
Inferred from Sequence Orthology
more info
 
involved_in synaptic vesicle endocytosis ISO
Inferred from Sequence Orthology
more info
 
involved_in tight junction assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Schaffer collateral - CA1 synapse ISO
Inferred from Sequence Orthology
more info
 
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
is_active_in actin filament IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in actin filament ISO
Inferred from Sequence Orthology
more info
 
located_in apical junction complex ISO
Inferred from Sequence Orthology
more info
 
located_in apical part of cell ISO
Inferred from Sequence Orthology
more info
 
located_in basal body patch ISO
Inferred from Sequence Orthology
more info
 
is_active_in calyx of Held ISO
Inferred from Sequence Orthology
more info
 
located_in cell-cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in dense body ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
part_of filamentous actin ISO
Inferred from Sequence Orthology
more info
 
located_in focal adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in myofibril ISO
Inferred from Sequence Orthology
more info
 
located_in phagocytic vesicle ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in postsynaptic actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
located_in postsynaptic actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in presynaptic actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
located_in presynaptic actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
actin, cytoplasmic 2
Names
actin, gamma, cytoplasmic 1
gamma-actin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127449.1NP_001120921.1  actin, cytoplasmic 2

    See identical proteins and their annotated locations for NP_001120921.1

    Status: VALIDATED

    Source sequence(s)
    CF110974, CK364554, CK595239
    UniProtKB/Swiss-Prot
    P63259
    Related
    ENSRNOP00000096150.1, ENSRNOT00000108494.1
    Conserved Domains (1) summary
    PTZ00281
    Location:1375
    PTZ00281; actin; Provisional

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051345.1 Reference mRatBN7.2 Primary Assembly

    Range
    105619738..105622587 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039085690.1XP_038941618.1  actin, cytoplasmic 2 isoform X1

    Conserved Domains (1) summary
    cl17037
    Location:1253
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
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