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Csta cystatin A [ Rattus norvegicus (Norway rat) ]

Gene ID: 288067, updated on 30-Sep-2021

Summary

Official Symbol
Cstaprovided by RGD
Official Full Name
cystatin Aprovided by RGD
Primary source
RGD:1309603
See related
EnsemblRapid:ENSRNOG00000068634
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Lung (RPKM 25.0), Testes (RPKM 2.8) and 1 other tissue See more
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Genomic context

See Csta in Genome Data Viewer
Location:
11q22
Exon count:
3
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (64620483..64631488)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (67555792..67566980)

Chromosome 11 - NC_051346.1Genomic Context describing neighboring genes Neighboring gene stefin-3-like Neighboring gene stefin A3-like 1 Neighboring gene U6 spliceosomal RNA Neighboring gene 40S ribosomal protein S2-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cysteine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cysteine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables cysteine-type endopeptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables protease binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in keratinocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of peptidase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of proteolysis ISO
Inferred from Sequence Orthology
more info
 
involved_in peptide cross-linking ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cornified envelope ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cystatin-A
Names
cystatin A (stefin A)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105876.1NP_001099346.1  cystatin-A

    See identical proteins and their annotated locations for NP_001099346.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473967
    UniProtKB/TrEMBL
    D3ZAJ1
    Related
    ENSRNOP00000077612.1, ENSRNOT00000118968.1
    Conserved Domains (1) summary
    pfam00031
    Location:491
    Cystatin; Cystatin domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051346.1 Reference mRatBN7.2 Primary Assembly

    Range
    64620483..64631488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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