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Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 288656, updated on 5-Mar-2024

Summary

Official Symbol
Arl6ip4provided by RGD
Official Full Name
ADP-ribosylation factor like GTPase 6 interacting protein 4provided by RGD
Primary source
RGD:1307657
See related
Ensembl:ENSRNOG00000001080 AllianceGenome:RGD:1307657
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nuclear speck and nucleolus. Orthologous to human ARL6IP4 (ADP ribosylation factor like GTPase 6 interacting protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 91.0), Kidney (RPKM 90.0) and 9 other tissues See more
Orthologs
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Genomic context

Location:
12q15
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (38140566..38142711, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (32479623..32481768, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (37904376..37906521, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene M-phase phosphoprotein 9 Neighboring gene phosphatidylinositol transfer protein, membrane-associated 2 Neighboring gene uncharacterized LOC134481294 Neighboring gene U6 spliceosomal RNA Neighboring gene 2-oxoglutarate and iron-dependent oxygenase domain containing 2 Neighboring gene ATP binding cassette subfamily B member 9

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC114409, MGC124687

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ADP-ribosylation factor-like protein 6-interacting protein 4
Names
ADP-ribosylation factor-like 6 interacting protein 4
ADP-ribosylation-like factor 6 interacting protein 4
ARL-6-interacting protein 4
aip-4
splicing factor SRrp37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025630.1NP_001020801.1  ADP-ribosylation factor-like protein 6-interacting protein 4

    See identical proteins and their annotated locations for NP_001020801.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097374
    UniProtKB/Swiss-Prot
    Q499T6, Q4V8I5
    UniProtKB/TrEMBL
    A6J113, A6J114
    Related
    ENSRNOP00000001432.4, ENSRNOT00000001432.6
    Conserved Domains (1) summary
    pfam10500
    Location:36229
    SR-25; Nuclear RNA-splicing-associated protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    38140566..38142711 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063271177.1XP_063127247.1  ADP-ribosylation factor-like protein 6-interacting protein 4 isoform X1