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HpVgp4 major capsid protein VP1 [ Mesocricetus auratus polyomavirus 1 ]

Gene ID: 29030994, updated on 18-Aug-2023

Summary

Gene symbol
HpVgp4
Gene description
major capsid protein VP1
Locus tag
HpVgp4
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mesocricetus auratus polyomavirus 1 (isolate: Berlin-Buch, nat-host: Mesocricetus auratus (Syrian hamster) strain Z3)
Lineage
Viruses; dsDNA viruses, no RNA stage; Polyomaviridae
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Genomic context

Sequence:
NC_001663.2 (2927..4093, complement)

NC_001663.2Genomic Context describing neighboring genes Neighboring gene small T antigen Neighboring gene middle T antigen Neighboring gene large T antigen Neighboring gene capsid protein VP3 Neighboring gene capsid protein VP2

General protein information

Preferred Names
major capsid protein VP1
YP_009111410.1
  • small T-antigen; promotes the efficient replication of genomic DNA; binds to and negativley regulates the function of protein phosphotase (PP2A) thereby accelerating the progression to S-phase; the small T-antigen shares a region in common with the large T-antigen known as the J-domain; the J-domain is required for multiple processes including assembly, viral genomic DNA replication and transcription; The polyomaviruses are non-enveloped dsDNA viruses; the viral genome is organized into two divergent transcriptional units known as early and late regions; mRNAs from the early region encode the viral small and large t-antigens; the small T antigen and large T antigen are expressed upon entry into the host nucleus early in the viral lifecycle; the small T antigen is not essential for replication in all cell lines

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001663.2 Reference assembly

    Range
    2927..4093 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009111410.1 major capsid protein VP1 [Mesocricetus auratus polyomavirus 1]

    See identical proteins and their annotated locations for YP_009111410.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7U3RXL1, I6VEK5, O73427
    Conserved Domains (1) summary
    PHA02614
    Location:5388
    PHA02614; Major capsid protein VP1; Provisional