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HpVgp1 large T antigen [ Mesocricetus auratus polyomavirus 1 ]

Gene ID: 29030997, updated on 18-Aug-2023

Summary

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Gene symbol
HpVgp1
Gene description
large T antigen
Locus tag
HpVgp1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mesocricetus auratus polyomavirus 1 (isolate: Berlin-Buch, nat-host: Mesocricetus auratus (Syrian hamster) strain Z3)
Lineage
Viruses; dsDNA viruses, no RNA stage; Polyomaviridae
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Genomic context

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Sequence:
NC_001663.2 (191..2885)

NC_001663.2Genomic Context describing neighboring genes Neighboring gene small T antigen Neighboring gene middle T antigen Neighboring gene major capsid protein VP1 Neighboring gene capsid protein VP3 Neighboring gene capsid protein VP2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001663.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Capsid protein-encoding genes of hamster polyomavirus and properties of the viral capsid. Siray H, et al. Virus Genes, 1999. PMID 10334036

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
large T antigen
YP_009111407.1
  • large T antigen; binds to the viral origin of replication; regulates the transcription of early region mRNA; helicase activity facilitates movement of the virion DNA replication fork; the small T antigen shares a region in common with the large T antigen known as the J-domain; the J-domain is required for multiple processes including assembly, viral genomic DNA replication and transcription; The polyomaviruses are non-enveloped dsDNA viruses; the viral genome is organized into two divergent transcriptional units known as early and late regions; mRNAs from the early region encode the viral small and large t-antigens; the small T antigen and large T antigen are expressed upon entry into the host nucleus early in the viral lifecycle

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001663.2 Reference assembly

    Range
    191..2885
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009111407.1 large T antigen [Mesocricetus auratus polyomavirus 1]

    See identical proteins and their annotated locations for YP_009111407.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7U3NIU3, I6VPL7
    Conserved Domains (4) summary
    smart00271
    Location:16 → 64
    DnaJ; DnaJ molecular chaperone homology domain
    PHA02624
    Location:1 → 757
    PHA02624; large T antigen; Provisional
    pfam02217
    Location:261 → 354
    T_Ag_DNA_bind; Origin of replication binding protein
    pfam06431
    Location:390 → 744
    Polyoma_lg_T_C; Polyomavirus large T antigen C-terminus
Nucleotide Protein
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