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BPyV_gp5 large T antigen [ Bos taurus polyomavirus 1 ]

Gene ID: 29031001, updated on 18-Aug-2023

Summary

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Gene symbol
BPyV_gp5
Gene description
large T antigen
Locus tag
BPyV_gp5
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus polyomavirus 1
Lineage
Viruses; dsDNA viruses, no RNA stage; Polyomaviridae; unassigned Polyomaviridae
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Genomic context

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Sequence:
NC_001442.1 (2690..4697, complement)

NC_001442.1Genomic Context describing neighboring genes Neighboring gene agnoprotein Neighboring gene VP2 Neighboring gene VP3 Neighboring gene major capsid protein VP1 Neighboring gene small t antigen

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001442.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The complete nucleotide sequence of bovine polyomavirus. Schuurman R, et al. J Gen Virol, 1990 Aug. PMID 2167926
  2. Analysis of splice sites in the early region of bovine polyomavirus: evidence for a unique pattern of large T mRNA splicing. Schuurman R, et al. J Gen Virol, 1992 Nov. PMID 1279101

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
large T antigen
NP_040788.2
  • large T antigen; binds to the viral origin of replication; regulates the transcription of early region mRNA; helicase activity facilitates movement of the virion DNA replication fork; the small T antigen shares a region in common with the large T antigen known as the J-domain; the J-domain is required for multiple processes including assembly, viral genomic DNA replication and transcription; The polyomaviruses are non-enveloped dsDNA viruses; the viral genome is organized into two divergent transcriptional units known as early and late regions; mRNAs from the early region encode the viral small and large t-antigens; the small T antigen and large T antigen are expressed upon entry into the host nucleus early in the viral lifecycle

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001442.1 Reference assembly

    Range
    2690..4697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_040788.2 large T antigen [Bos taurus polyomavirus 1]

    See identical proteins and their annotated locations for NP_040788.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P24851, Q84248, Q90051
    UniProtKB/TrEMBL
    A0A097IQW1, A0A0S2SW02, A0A0U3SBE6
    Conserved Domains (1) summary
    PHA02624
    Location:1 → 619
    PHA02624; large T antigen; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P24851.2

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