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Tktl2 transketolase-like 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 290685, updated on 30-Sep-2021

Summary

Official Symbol
Tktl2provided by RGD
Official Full Name
transketolase-like 2provided by RGD
Primary source
RGD:1304767
See related
EnsemblRapid:ENSRNOG00000014185
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1304767
Expression
Restricted expression toward (RPKM 111.7) See more
Orthologs
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Genomic context

See Tktl2 in Genome Data Viewer
Location:
16p14
Exon count:
2
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (23202460..23209741, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (24944197..24951478, complement)

Chromosome 16 - NC_051351.1Genomic Context describing neighboring genes Neighboring gene neuropeptide Y receptor Y5 Neighboring gene U7 small nuclear RNA Neighboring gene membrane associated ring-CH-type finger 1 Neighboring gene translation machinery associated 16 homolog Neighboring gene 60S ribosomal protein L22-like 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables thiamine pyrophosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transketolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
transketolase-like protein 2
NP_001099550.1
XP_006253084.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106080.1NP_001099550.1  transketolase-like protein 2

    See identical proteins and their annotated locations for NP_001099550.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474045
    UniProtKB/TrEMBL
    D3ZHE7
    Conserved Domains (4) summary
    cd07033
    Location:324479
    TPP_PYR_DXS_TK_like; Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins
    PRK05899
    Location:17623
    PRK05899; transketolase; Reviewed
    cd02012
    Location:22272
    TPP_TK; Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the ...
    pfam02780
    Location:495617
    Transketolase_C; Transketolase, C-terminal domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051351.1 Reference mRatBN7.2 Primary Assembly

    Range
    23202460..23209741 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006253022.3XP_006253084.1  transketolase-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006253084.1

    UniProtKB/TrEMBL
    D3ZHE7
    Related
    ENSRNOP00000018987.1, ENSRNOT00000018987.4
    Conserved Domains (4) summary
    cd07033
    Location:324479
    TPP_PYR_DXS_TK_like; Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins
    PRK05899
    Location:17623
    PRK05899; transketolase; Reviewed
    cd02012
    Location:22272
    TPP_TK; Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the ...
    pfam02780
    Location:495617
    Transketolase_C; Transketolase, C-terminal domain
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