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Slc35d2 solute carrier family 35 member D2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 290959, updated on 13-Apr-2024

Summary

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Official Symbol
Slc35d2provided by RGD
Official Full Name
solute carrier family 35 member D2provided by RGD
Primary source
RGD:1309518
See related
Ensembl:ENSRNOG00000027229 AllianceGenome:RGD:1309518
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable antiporter activity and pyrimidine nucleotide-sugar transmembrane transporter activity. Predicted to be involved in UDP-N-acetylgalactosamine transmembrane transport; UDP-N-acetylglucosamine transmembrane transport; and UDP-glucuronic acid transmembrane transport. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Orthologous to human SLC35D2 (solute carrier family 35 member D2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 61.1), Lung (RPKM 31.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Slc35d2 in Genome Data Viewer
Location:
17p14
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (992153..1025476)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (987899..1019747)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (1618641..1649734, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene hyaluronan binding protein 4 Neighboring gene zinc finger protein 367 Neighboring gene hydroxysteroid (17-beta) dehydrogenase 3 Neighboring gene ERCC excision repair 6 like 2 Neighboring gene uncharacterized LOC102554174

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables UDP-N-acetylgalactosamine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-N-acetylglucosamine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glucuronic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleotide-sugar transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in GDP-fucose transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in UDP-N-acetylgalactosamine transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in UDP-N-acetylglucosamine transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in UDP-glucuronic acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_positive_effect heparan sulfate proteoglycan biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in nucleotide-sugar transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
is_active_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
nucleotide sugar transporter SLC35D2
Names
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106098.2 → NP_001099568.2  nucleotide sugar transporter SLC35D2

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    D4A1T9
    Related
    ENSRNOP00000038617.4, ENSRNOT00000036212.7
    Conserved Domains (1) summary
    cl26744
    Location:16 → 301
    TPT; Triose-phosphate Transporter family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    992153..1025476
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006253493.5 → XP_006253555.1  nucleotide sugar transporter SLC35D2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AC44
    Related
    ENSRNOP00000091466.1
    Conserved Domains (2) summary
    pfam03151
    Location:16 → 207
    TPT; Triose-phosphate Transporter family
    cl23754
    Location:102 → 174
    EamA; EamA-like transporter family

  2. XM_039095438.2 → XP_038951366.1  nucleotide sugar transporter SLC35D2 isoform X3

    Conserved Domains (1) summary
    cl26744
    Location:16 → 186
    TPT; Triose-phosphate Transporter family

  3. XM_039095437.2 → XP_038951365.1  nucleotide sugar transporter SLC35D2 isoform X2

    Conserved Domains (1) summary
    cl26744
    Location:17 → 210
    TPT; Triose-phosphate Transporter family
Nucleotide Protein Strain
Heading Accession and Version

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