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Drc7 dynein regulatory complex subunit 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291853, updated on 5-Mar-2024

Summary

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Official Symbol
Drc7provided by RGD
Official Full Name
dynein regulatory complex subunit 7provided by RGD
Primary source
RGD:1565601
See related
Ensembl:ENSRNOG00000025860 AllianceGenome:RGD:1565601
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ccdc135; RGD1565601
Summary
Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm. Predicted to be active in motile cilium. Orthologous to human DRC7 (dynein regulatory complex subunit 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 55.4) and Lung (RPKM 18.7) See more
Orthologs
human mouse all
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Genomic context

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See Drc7 in Genome Data Viewer
Location:
19p13
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (9949484..9967296, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (9943452..9961266, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (10363012..10380822, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene kinesin family member C3 Neighboring gene uncharacterized LOC134483686 Neighboring gene katanin regulatory subunit B1 Neighboring gene adhesion G protein-coupled receptor G3 Neighboring gene adhesion G protein-coupled receptor G1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in flagellated sperm motility IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in flagellated sperm motility ISO
Inferred from Sequence Orthology
more info
  
involved_in sperm axoneme assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in spermatogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
is_active_in motile cilium IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
dynein regulatory complex subunit 7
Names
coiled-coil domain containing 135
coiled-coil domain-containing protein 135
coiled-coil domain-containing protein lobo homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106169.1 → NP_001099639.1  dynein regulatory complex subunit 7

    See identical proteins and their annotated locations for NP_001099639.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474006
    UniProtKB/TrEMBL
    A6JY30, D3ZZ82
    Related
    ENSRNOP00000032646.4, ENSRNOT00000031064.6
    Conserved Domains (1) summary
    pfam01841
    Location:174 → 211
    Transglut_core; Transglutaminase-like superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    9949484..9967296 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006255081.5 → XP_006255143.1  dynein regulatory complex subunit 7 isoform X2

    Conserved Domains (1) summary
    PRK10246
    Location:674 → 856
    PRK10246; exonuclease subunit SbcC; Provisional

  2. XM_006255079.5 → XP_006255141.1  dynein regulatory complex subunit 7 isoform X1

    See identical proteins and their annotated locations for XP_006255141.1

    UniProtKB/TrEMBL
    A6JY30, D3ZZ82
    Conserved Domains (1) summary
    pfam01841
    Location:174 → 211
    Transglut_core; Transglutaminase-like superfamily

RNA

  1. XR_005496624.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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