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Adgrg3 adhesion G protein-coupled receptor G3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291854, updated on 11-Apr-2024

Summary

Official Symbol
Adgrg3provided by RGD
Official Full Name
adhesion G protein-coupled receptor G3provided by RGD
Primary source
RGD:1305674
See related
Ensembl:ENSRNOG00000014896 AllianceGenome:RGD:1305674
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gpr97
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of CREB transcription factor activity; and negative regulation of NIK/NF-kappaB signaling. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human ADGRG3 (adhesion G protein-coupled receptor G3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 11.6), Spleen (RPKM 8.4) and 8 other tissues See more
Orthologs
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Genomic context

Location:
19p13
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (9978450..10007145, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (9972425..10001118, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (10392001..10422606, complement)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene katanin regulatory subunit B1 Neighboring gene dynein regulatory complex subunit 7 Neighboring gene adhesion G protein-coupled receptor G1 Neighboring gene adhesion G protein-coupled receptor G5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
probable G-protein coupled receptor 97; adhesion G protein-coupled receptor G3
Names
G protein-coupled receptor 97

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    9978450..10007145 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006255127.5XP_006255189.1  adhesion G protein-coupled receptor G3 isoform X4

    See identical proteins and their annotated locations for XP_006255189.1

    UniProtKB/TrEMBL
    A6JY31
    Conserved Domains (2) summary
    pfam01825
    Location:167206
    GPS; GPCR proteolysis site, GPS, motif
    cl21561
    Location:216465
    7tm_4; Olfactory receptor
  2. XM_006255126.5XP_006255188.1  adhesion G protein-coupled receptor G3 isoform X2

    See identical proteins and their annotated locations for XP_006255188.1

    UniProtKB/TrEMBL
    A0A0G2JSN6, A6JY31
    Related
    ENSRNOP00000020062.5
    Conserved Domains (2) summary
    pfam01825
    Location:216255
    GPS; GPCR proteolysis site, GPS, motif
    cl21561
    Location:265514
    7tm_4; Olfactory receptor
  3. XM_039098149.1XP_038954077.1  adhesion G protein-coupled receptor G3 isoform X3

    UniProtKB/TrEMBL
    A6JY31
    Conserved Domains (3) summary
    pfam01825
    Location:195233
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:245270
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:243502
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  4. XM_039098148.1XP_038954076.1  adhesion G protein-coupled receptor G3 isoform X1

    UniProtKB/TrEMBL
    A6JY31
    Conserved Domains (3) summary
    pfam01825
    Location:244282
    GPS; GPCR proteolysis site, GPS, motif
    cd14964
    Location:294319
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:292551
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily