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Csn3 casein kappa [ Rattus norvegicus (Norway rat) ]

Gene ID: 29188, updated on 13-Apr-2024

Summary

Official Symbol
Csn3provided by RGD
Official Full Name
casein kappaprovided by RGD
Primary source
RGD:61990
See related
Ensembl:ENSRNOG00000001951 AllianceGenome:RGD:61990
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Csnk; Csn10
Summary
Predicted to be involved in lactation and protein stabilization. Predicted to be active in extracellular space. Orthologous to human CSN3 (casein kappa). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 25.8), Testes (RPKM 4.5) and 1 other tissue See more
Orthologs
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Genomic context

Location:
14p21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (20433277..20439830, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (20154032..20160585, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (21803738..21810291, complement)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene calcium binding protein, spermatid associated 1 Neighboring gene mucin-5AC-like Neighboring gene uncharacterized LOC120096584 Neighboring gene follicular dendritic cell secreted protein Neighboring gene uncharacterized LOC108352727 Neighboring gene odontogenic, ameloblast associated

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in lactation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within lactation ISO
Inferred from Sequence Orthology
more info
 
involved_in lactation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein stabilization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031562.2NP_113750.1  kappa-casein precursor

    See identical proteins and their annotated locations for NP_113750.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/Swiss-Prot
    P04468
    UniProtKB/TrEMBL
    A6KU13
    Related
    ENSRNOP00000002671.2, ENSRNOT00000002671.4
    Conserved Domains (1) summary
    pfam00997
    Location:22177
    Casein_kappa; Kappa casein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    20433277..20439830 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)