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Rps14 ribosomal protein S14 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29284, updated on 11-Apr-2024

Summary

Official Symbol
Rps14provided by RGD
Official Full Name
ribosomal protein S14provided by RGD
Primary source
RGD:62025
See related
Ensembl:ENSRNOG00000018774 AllianceGenome:RGD:62025
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
A structural constituent of ribosome. Involved in ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in chromosome 5q deletion syndrome. Orthologous to human RPS14 (ribosomal protein S14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 6995.9), Thymus (RPKM 5233.2) and 9 other tissues See more
Orthologs
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Genomic context

Location:
18q12.1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (56492010..56503092)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (54227854..54232638)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (56042532..56047316)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098275 Neighboring gene N-deacetylase and N-sulfotransferase 1 Neighboring gene CD74 molecule Neighboring gene treacle ribosome biogenesis factor 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables mRNA 5'-UTR binding ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
enables translation regulator activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translation ISO
Inferred from Sequence Orthology
more info
 
involved_in erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in maturation of SSU-rRNA ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal small subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ribosomal small subunit assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ribosomal small subunit assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
 
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
small ribosomal subunit protein uS11
Names
40S ribosomal protein S14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022672.1NP_073163.1  small ribosomal subunit protein uS11

    See identical proteins and their annotated locations for NP_073163.1

    Status: PROVISIONAL

    Source sequence(s)
    X15040
    UniProtKB/Swiss-Prot
    P13471
    Related
    ENSRNOP00000056260.1, ENSRNOT00000059501.3
    Conserved Domains (1) summary
    PTZ00129
    Location:1140
    PTZ00129; 40S ribosomal protein S14; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    56492010..56503092
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063277276.1XP_063133346.1  small ribosomal subunit protein uS11 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A3Z2
  2. XM_063277277.1XP_063133347.1  small ribosomal subunit protein uS11 isoform X2

    UniProtKB/TrEMBL
    A6IXC6, A6IXC8, Q6PDV6