U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ahsp alpha hemoglobin stabilizing protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 293522, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Ahspprovided by RGD
Official Full Name
alpha hemoglobin stabilizing proteinprovided by RGD
Primary source
RGD:1306725
See related
AllianceGenome:RGD:1306725
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Eraf
Summary
Predicted to enable hemoglobin binding activity. Predicted to be involved in erythrocyte differentiation; protein folding; and protein stabilization. Predicted to be active in cytoplasm. Orthologous to human AHSP (alpha hemoglobin stabilizing protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 4235.6) See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ahsp in Genome Data Viewer
Location:
1q37
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (192310306..192315943)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (182879901..182885508)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (199720038..199721010)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene transforming growth factor beta 1 induced transcript 1 Neighboring gene solute carrier family 5 member 2 Neighboring gene RUS family member 1 Neighboring gene uncharacterized LOC120099940 Neighboring gene uncharacterized LOC134485178 Neighboring gene uncharacterized LOC103691239

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. An abundant erythroid protein that stabilizes free alpha-haemoglobin. Kihm AJ, et al. Nature, 2002 Jun 13. PMID 12066189
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables hemoglobin binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in erythrocyte differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein folding ISO
Inferred from Sequence Orthology
more info
  
involved_in protein stabilization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein stabilization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
alpha-hemoglobin-stabilizing protein
Names
erythroid associated factor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106299.1 → NP_001099769.1  alpha-hemoglobin-stabilizing protein

    See identical proteins and their annotated locations for NP_001099769.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473956
    UniProtKB/TrEMBL
    A9UMW3
    Conserved Domains (1) summary
    pfam09236
    Location:5 → 91
    AHSP; Alpha-haemoglobin stabilizing protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    192310306..192315943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039107525.2 → XP_038963453.1  alpha-hemoglobin-stabilizing protein isoform X1

    UniProtKB/TrEMBL
    A9UMW3
    Conserved Domains (1) summary
    pfam09236
    Location:5 → 91
    AHSP; Alpha-haemoglobin stabilizing protein

  2. XM_063286306.1 → XP_063142376.1  alpha-hemoglobin-stabilizing protein isoform X1

    UniProtKB/TrEMBL
    A9UMW3
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools