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Map1b microtubule-associated protein 1B [ Rattus norvegicus (Norway rat) ]

Gene ID: 29456, updated on 30-Sep-2021

Summary

Official Symbol
Map1bprovided by RGD
Official Full Name
microtubule-associated protein 1Bprovided by RGD
Primary source
RGD:3043
See related
EnsemblRapid:ENSRNOG00000017428
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mtap1b
Summary
binds microtubules and may function as microtubule cross-linkers [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 1000.6), Heart (RPKM 118.4) and 4 other tissues See more
Orthologs
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Genomic context

See Map1b in Genome Data Viewer
Location:
2q12
Exon count:
8
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (30817261..30910458, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (29675391..29768750, complement)

Chromosome 2 - NC_051337.1Genomic Context describing neighboring genes Neighboring gene pentatricopeptide repeat domain 2 Neighboring gene mitochondrial ribosomal protein S27 Neighboring gene uncharacterized LOC102553545 Neighboring gene hypothetical LOC499517

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables actin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables actin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables microtubule binding IDA
Inferred from Direct Assay
more info
PubMed 
enables microtubule binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables phospholipid binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-containing complex binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within axon extension ISO
Inferred from Sequence Orthology
more info
 
involved_in axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within axonogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular process ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to growth factor stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to peptide hormone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in dendrite development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within dendrite development ISO
Inferred from Sequence Orthology
more info
 
involved_in developmental maturation IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within establishment of monopolar cell polarity ISO
Inferred from Sequence Orthology
more info
 
involved_in induction of synaptic plasticity by chemical substance IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in microtubule bundle formation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within microtubule bundle formation ISO
Inferred from Sequence Orthology
more info
 
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within mitochondrion transport along microtubule ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of intracellular transport ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of microtubule depolymerization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in nervous system development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in neuron development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in peripheral nervous system axon regeneration IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in positive regulation of axon extension IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of microtubule polymerization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of microtubule depolymerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in response to axon injury IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to carbohydrate IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to estradiol IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to inorganic substance IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to insecticide IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to mechanical stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to nutrient levels IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to vitamin A IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to wounding IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to xenobiotic stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in synapse assembly IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in apical dendrite IDA
Inferred from Direct Assay
more info
PubMed 
located_in axon IDA
Inferred from Direct Assay
more info
PubMed 
located_in basal dendrite IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in dendrite IDA
Inferred from Direct Assay
more info
PubMed 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 
located_in growth cone IDA
Inferred from Direct Assay
more info
PubMed 
located_in hippocampal mossy fiber IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in microtubule IDA
Inferred from Direct Assay
more info
PubMed 
part_of microtubule associated complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of microtubule associated complex IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in perikaryon IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in photoreceptor outer segment ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
located_in somatodendritic compartment IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in varicosity IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
microtubule-associated protein 1B
Names
MAP-1B
neuraxin

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019217.1NP_062090.1  microtubule-associated protein 1B

    Status: PROVISIONAL

    Source sequence(s)
    AA925503, BF286433, BG378086, BG665276, CA503854, CA510735, CA510940, CB576609, CB579120, CB580055, CB583564, CB584802, CB610210, CB810012, CF977184, CO393350, X60370
    UniProtKB/Swiss-Prot
    P15205
    Related
    ENSRNOP00000023460.5, ENSRNOT00000023460.6
    Conserved Domains (3) summary
    PTZ00121
    Location:5311158
    PTZ00121; MAEBL; Provisional
    PHA03247
    Location:20952348
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:15431875
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051337.1 Reference mRatBN7.2 Primary Assembly

    Range
    30817261..30910458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039101889.1XP_038957817.1  microtubule-associated protein 1B isoform X1

    Conserved Domains (3) summary
    PTZ00121
    Location:4051032
    PTZ00121; MAEBL; Provisional
    PHA03247
    Location:19692222
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:14171749
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
  2. XM_039101890.1XP_038957818.1  microtubule-associated protein 1B isoform X2

    Conserved Domains (1) summary
    PTZ00121
    Location:5311158
    PTZ00121; MAEBL; Provisional
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