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Glmp glycosylated lysosomal membrane protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 295231, updated on 5-Mar-2024

Summary

Official Symbol
Glmpprovided by RGD
Official Full Name
glycosylated lysosomal membrane proteinprovided by RGD
Primary source
RGD:1303130
See related
Ensembl:ENSRNOG00000019281 AllianceGenome:RGD:1303130
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1303130; 0610031j06rik
Summary
Predicted to be involved in positive regulation of transcription by RNA polymerase II; protein localization to lysosome; and protein stabilization. Predicted to be located in cytosol and nucleus. Predicted to be integral component of membrane. Predicted to be active in lysosome. Orthologous to human GLMP (glycosylated lysosomal membrane protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 301.1), Adrenal (RPKM 157.7) and 9 other tissues See more
Orthologs
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Genomic context

Location:
2q34
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176092098..176095688)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173794273..173797863)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187697528..187701118)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene chaperonin containing TCP1 subunit 3 Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene ATP synthase subunit g, mitochondrial pseudogene Neighboring gene transmembrane protein 79 Neighboring gene SMG5 nonsense mediated mRNA decay factor

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC94430

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to lysosome ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to lysosome ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
 
involved_in protein stabilization ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
glycosylated lysosomal membrane protein
Names
kidney predominant protein NCU-G1
lysosomal protein NCU-G1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004226.1NP_001004226.1  glycosylated lysosomal membrane protein precursor

    See identical proteins and their annotated locations for NP_001004226.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079294
    UniProtKB/Swiss-Prot
    Q68FV6
    UniProtKB/TrEMBL
    A0A8I6ADT3, A6J663
    Related
    ENSRNOP00000026152.4, ENSRNOT00000026153.6
    Conserved Domains (1) summary
    pfam15065
    Location:54379
    NCU-G1; Lysosomal transcription factor, NCU-G1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    176092098..176095688
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)