U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

UL31 nuclear egress lamina protein [ Suid alphaherpesvirus 1 ]

Gene ID: 2952498, updated on 18-Aug-2023

Summary

Go to the top of the page Help
Gene symbol
UL31
Gene description
nuclear egress lamina protein
Locus tag
SuHV1_gp18
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Suid alphaherpesvirus 1 (strain: Composite of 6 strains, acronym: PRV, acronym: SuHV-1, nat-host: Sus scrofa)
Lineage
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_006151.1 (28599..29614, complement)

NC_006151.1Genomic Context describing neighboring genes Neighboring gene envelope glycoprotein B Neighboring gene DNA packaging terminase subunit 2 Neighboring gene single-stranded DNA-binding protein Neighboring gene DNA polymerase catalytic subunit Neighboring gene DNA packaging protein UL32 Neighboring gene DNA packaging protein UL33 Neighboring gene nuclear egress membrane protein Neighboring gene small capsid protein Neighboring gene large tegument protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_006151.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Function of the Nonconserved N-Terminal Domain of Pseudorabies Virus pUL31 in Nuclear Egress. Klupp BG, et al. J Virol, 2018 Aug 1. PMID 29793954, Free PMC Article
  2. Identification of molecular determinants for the nuclear import of pseudorabies virus UL31. Li M, et al. Arch Biochem Biophys, 2015 Dec 1. PMID 26450651
  3. Characterization of the nuclear import and export signals of pseudorabies virus UL31. Li M, et al. Arch Virol, 2015 Oct. PMID 26195191
  4. Functional characterization of nuclear trafficking signals in pseudorabies virus pUL31. Paßvogel L, et al. J Virol, 2015 Feb. PMID 25505082, Free PMC Article
  5. A single herpesvirus protein can mediate vesicle formation in the nuclear envelope. Lorenz M, et al. J Biol Chem, 2015 Mar 13. PMID 25605719, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. data show that neither the bipartite NLS nor the predicted phosphorylation sites are essential for pUL31 function during nuclear egress. Moreover, nearly the complete variable N-terminal part was dispensable for function as long as a stretch of basic amino acids was retained.
    Title: Function of the Nonconserved N-Terminal Domain of Pseudorabies Virus pUL31 in Nuclear Egress.
  2. The nuclear import of UL31 was found to be dependent on the Ran-, importin alpha1-, alpha3-, alpha5-, alpha7-, beta1-and transportin-1-mediated pathway.
    Title: Identification of molecular determinants for the nuclear import of pseudorabies virus UL31.
  3. Amino acids 4 to 20 (RRRLLRRKSSAARRKTL) and aa 21 to 34 (TRAARDRYAPYFAY)are nuclear import and export signals of UL31.
    Title: Characterization of the nuclear import and export signals of pseudorabies virus UL31.
  4. Using giant unilamellar vesicles, this work reconstitutes the function of two viral proteins, pUL31 and pUL34, in nuclear envelope vesicle formation. pUL34 recruits pUL31 to the membrane, which deforms membranes to produce nuclear envelope vesicles.
    Title: A single herpesvirus protein can mediate vesicle formation in the nuclear envelope.
  5. The N terminus of pUL31 is required for efficient nuclear targeting but not for pUL34 interaction, while the C terminus is required for complex formation and efficient budding of viral capsids at the inner nuclear membrane.
    Title: Functional characterization of nuclear trafficking signals in pseudorabies virus pUL31.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

regulatory

  • Loc: c28620-28615 inference = ab initio prediction:PolyADQ: , regulatory_class = polyA_signal_sequence
  • Loc: c29614-29608 inference = ab initio prediction:TRANSFACFind: , regulatory_class = TATA_box

General protein information

Go to the top of the page Help
Preferred Names
nuclear egress lamina protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_006151.1 Reference assembly

    Range
    28599..29614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_068334.1 nuclear egress lamina protein [Suid alphaherpesvirus 1]

    See identical proteins and their annotated locations for YP_068334.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A172XDD4, G3G955, Q5PPC3, Q911V7
    Conserved Domains (1) summary
    PHA03328
    Location:11 → 270
    PHA03328; nuclear egress lamina protein UL31; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.