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Bpgm bisphosphoglycerate mutase [ Rattus norvegicus (Norway rat) ]

Gene ID: 296973, updated on 2-Oct-2021

Summary

Official Symbol
Bpgmprovided by RGD
Official Full Name
bisphosphoglycerate mutaseprovided by RGD
Primary source
RGD:735018
See related
EnsemblRapid:ENSRNOG00000010133
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ab2-098
Summary
human homolog is a trifunctional enzyme which displays synthase, mutase, and phosphatase activities [RGD, Feb 2006]
Expression
Biased expression in Spleen (RPKM 880.3), Muscle (RPKM 473.0) and 9 other tissues See more
Orthologs
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Genomic context

See Bpgm in Genome Data Viewer
Location:
4q22
Exon count:
6
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (63139730..63168581)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (61912210..61940697)

Chromosome 4 - NC_051339.1Genomic Context describing neighboring genes Neighboring gene myosin light polypeptide 6-like Neighboring gene aldo-keto reductase family 1 member B10 Neighboring gene aldo-keto reductase family 1, member B7 Neighboring gene uncharacterized LOC120102253 Neighboring gene caldesmon 1 Neighboring gene uncharacterized LOC120102254

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables bisphosphoglycerate mutase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables phosphoglycerate mutase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in erythrocyte development IDA
Inferred from Direct Assay
more info
PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
bisphosphoglycerate mutase
Names
2,3-bisphosphoglycerate mutase
NP_955414.1
XP_006236321.1
XP_038963221.1
XP_038963222.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199382.2NP_955414.1  bisphosphoglycerate mutase

    See identical proteins and their annotated locations for NP_955414.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000141
    UniProtKB/TrEMBL
    Q6P6G4
    Related
    ENSRNOP00000013566.4, ENSRNOT00000013569.5
    Conserved Domains (1) summary
    cl11399
    Location:4253
    HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051339.1 Reference mRatBN7.2 Primary Assembly

    Range
    63139730..63168581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039107293.1XP_038963221.1  bisphosphoglycerate mutase isoform X1

    Conserved Domains (1) summary
    cl11399
    Location:4253
    HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
  2. XM_039107294.1XP_038963222.1  bisphosphoglycerate mutase isoform X1

    Conserved Domains (1) summary
    cl11399
    Location:4253
    HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
  3. XM_006236259.4XP_006236321.1  bisphosphoglycerate mutase isoform X1

    See identical proteins and their annotated locations for XP_006236321.1

    UniProtKB/TrEMBL
    Q6P6G4
    Conserved Domains (1) summary
    cl11399
    Location:4253
    HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
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