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Zbtb8os zinc finger and BTB domain containing 8 opposite strand [ Rattus norvegicus (Norway rat) ]

Gene ID: 297885, updated on 13-Apr-2024

Summary

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Official Symbol
Zbtb8osprovided by RGD
Official Full Name
zinc finger and BTB domain containing 8 opposite strandprovided by RGD
Primary source
RGD:1562249
See related
Ensembl:ENSRNOG00000008226 AllianceGenome:RGD:1562249
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562249; Zbtb8os-ps1
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be part of tRNA-splicing ligase complex. Orthologous to human ZBTB8OS (zinc finger and BTB domain containing 8 opposite strand). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 244.2), Adrenal (RPKM 168.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
5q36
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (146959939..146971389)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (141675595..141687148)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (147535584..147547252)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein uL23-like Neighboring gene syncoilin, intermediate filament protein Neighboring gene RB binding protein 4, chromatin remodeling factor Neighboring gene uncharacterized LOC120103131 Neighboring gene zinc finger and BTB domain containing 8a Neighboring gene small nucleolar RNA SNORA70

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors. Popow J, et al. Nature, 2014 Jul 3. PMID 24870230, Free PMC Article
  2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tRNA splicing, via endonucleolytic cleavage and ligation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA splicing, via endonucleolytic cleavage and ligation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of tRNA-splicing ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of tRNA-splicing ligase complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein archease
Names
zinc finger and BTB domain containing 8 opposite strand, pseudogene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399489.1 → NP_001386418.1  protein archease isoform 1

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    M0R5Y9
    Related
    ENSRNOP00000064823.1, ENSRNOT00000074628.4
    Conserved Domains (1) summary
    pfam01951
    Location:31 → 167
    Archease; Archease protein family (MTH1598/TM1083)

  2. NM_001399490.1 → NP_001386419.1  protein archease isoform 2

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A6ISI4
    Conserved Domains (1) summary
    pfam01951
    Location:1 → 110
    Archease; Archease protein family (MTH1598/TM1083)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    146959939..146971389
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039111528.2 → XP_038967456.1  protein archease isoform X1

    UniProtKB/TrEMBL
    A6ISI4
    Conserved Domains (1) summary
    pfam01951
    Location:1 → 110
    Archease; Archease protein family (MTH1598/TM1083)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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