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Inip INTS3 and NABP interacting protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 298032, updated on 4-Apr-2024

Summary

Official Symbol
Inipprovided by RGD
Official Full Name
INTS3 and NABP interacting proteinprovided by RGD
Primary source
RGD:1307983
See related
Ensembl:ENSRNOG00000069187 AllianceGenome:RGD:1307983
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307983
Summary
Predicted to be involved in DNA repair and response to ionizing radiation. Predicted to be located in nucleus and site of double-strand break. Predicted to be part of SOSS complex. Predicted to be active in nucleoplasm. Orthologous to human INIP (INTS3 and NABP interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 120.5), Spleen (RPKM 89.2) and 9 other tissues See more
Orthologs
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Genomic context

Location:
5q24
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (79443317..79457552, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (74648392..74662628, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (77016871..77031106, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486941 Neighboring gene KIAA1958 homolog Neighboring gene uncharacterized LOC120102886 Neighboring gene transfer RNA serine (anticodon AGA) 22 Neighboring gene sorting nexin family member 30 Neighboring gene transfer RNA alanine (anticodon AGC) 81

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in DNA damage response ISO
Inferred from Sequence Orthology
more info
 
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in DNA repair ISO
Inferred from Sequence Orthology
more info
 
involved_in double-strand break repair via homologous recombination ISO
Inferred from Sequence Orthology
more info
 
involved_in mitotic G2/M transition checkpoint ISO
Inferred from Sequence Orthology
more info
 
involved_in response to ionizing radiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of SOSS complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of SOSS complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in site of double-strand break ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305282.3NP_001292211.1  SOSS complex subunit C

    See identical proteins and their annotated locations for NP_001292211.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A0A8I5ZKB5, A6KDX4, D3Z914
    Related
    ENSRNOP00000094143.1, ENSRNOT00000114117.1
    Conserved Domains (1) summary
    pfam15925
    Location:18101
    SOSSC; SOSS complex subunit C

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    79443317..79457552 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)