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Mup5 major urinary protein 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 298107, updated on 13-Apr-2024

Summary

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Official Symbol
Mup5provided by RGD
Official Full Name
major urinary protein 5provided by RGD
Primary source
RGD:735107
See related
Ensembl:ENSRNOG00000067602 AllianceGenome:RGD:735107
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
PGCL6
Summary
Predicted to enable pheromone binding activity and small molecule binding activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 14142.4) See more
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Genomic context

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Location:
5q24
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (79996023..79999893, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (75201324..75204903, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (77744217..77903161, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene major urinary protein 4, pseudogene 8 Neighboring gene major urinary protein-like Neighboring gene zinc finger protein 37-like Neighboring gene major urinary protein-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The evolutionary history of the SAL1 gene family in eutherian mammals. Meslin C, et al. BMC Evol Biol, 2011 May 28. PMID 21619679, Free PMC Article
  2. Molecular evidence of complex tissue- and sex-specific mRNA expression of the rat alpha(2u)-globulin multigene family. Saito K, et al. Biochem Biophys Res Commun, 2000 Jun 7. PMID 10833415
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables endopeptidase inhibitor activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables pheromone binding IEA
Inferred from Electronic Annotation
more info
  
enables small molecule binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
major urinary protein 5
Names
alpha-2u globulin PGCL5
alpha-2u globulin PGCL6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203325.2 → NP_976070.2  major urinary protein 5 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A6KDY3
    Related
    ENSRNOP00000093267.1, ENSRNOT00000116257.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    79996023..79999893 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039109478.2 → XP_038965406.1  major urinary protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AJN1, Q9JJI1
    Conserved Domains (1) summary
    cd19428
    Location:69 → 224
    lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_147213.1: Suppressed sequence

    Description
    NM_147213.1: This RefSeq was removed because it is redundant with another RefSeq.
Nucleotide Protein Strain
Heading Accession and Version

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