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Ifi27l2b interferon, alpha-inducible protein 27 like 2B [ Rattus norvegicus (Norway rat) ]

Gene ID: 299269, updated on 29-Feb-2024

Summary

Official Symbol
Ifi27l2bprovided by RGD
Official Full Name
interferon, alpha-inducible protein 27 like 2Bprovided by RGD
Primary source
RGD:1559721
See related
Ensembl:ENSRNOG00000026605 AllianceGenome:RGD:1559721
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
isg12(b)
Summary
Predicted to be involved in apoptotic signaling pathway. Predicted to act upstream of or within aging and response to virus. Predicted to be located in mitochondrial membrane. Predicted to be active in mitochondrion. Orthologous to several human genes including IFI27L2 (interferon alpha inducible protein 27 like 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 2563.8), Liver (RPKM 2484.2) and 7 other tissues See more
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Genomic context

Location:
6q32
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (128363658..128365144, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (122598872..122600358, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (127336305..127337791, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene DEAD-box helicase 24 Neighboring gene interferon, alpha-inducible protein 27 Neighboring gene uncharacterized LOC108351293 Neighboring gene protein phosphatase 4, regulatory subunit 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within response to virus ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in mitochondrial membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
interferon alpha-inducible protein 27-like protein 2B
Names
ISG12(b) protein-like
putative ISG12(b) protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_206846.2NP_996728.1  interferon alpha-inducible protein 27-like protein 2B

    See identical proteins and their annotated locations for NP_996728.1

    Status: PROVISIONAL

    Source sequence(s)
    BN000240
    UniProtKB/TrEMBL
    B2RYR1, F7FIE2, Q6IEA8
    Related
    ENSRNOP00000035385.6, ENSRNOT00000032015.6
    Conserved Domains (1) summary
    pfam06140
    Location:2782
    Ifi-6-16; Interferon-induced 6-16 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    128363658..128365144 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)