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Serpina6 serpin family A member 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299270, updated on 30-Sep-2021

Summary

Official Symbol
Serpina6provided by RGD
Official Full Name
serpin family A member 6provided by RGD
Primary source
RGD:1595901
See related
EnsemblRapid:ENSRNOG00000009438
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Cbg
Expression
Restricted expression toward (RPKM 3523.6) See more
Orthologs
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Genomic context

See Serpina6 in Genome Data Viewer
Location:
6q32
Exon count:
5
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (122780040..122790274, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (127523948..127534178, complement)

Chromosome 6 - NC_051341.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 4, regulatory subunit 4 Neighboring gene serpin family A member 10 Neighboring gene serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16 Neighboring gene serpin family A member 1F Neighboring gene similar to Alpha-1-antitrypsin-related protein precursor

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Clone Names

  • MGC112780

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables serine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables steroid binding ISO
Inferred from Sequence Orthology
more info
 
enables steroid binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
acts_upstream_of_or_within glucocorticoid metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
corticosteroid-binding globulin
Names
Corticosteroid binding globulin
serine (or cysteine) peptidase inhibitor, clade A, member 6
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
serpin A6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
serpin peptidase inhibitor, clade A, member 6
transcortin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009663.1NP_001009663.1  corticosteroid-binding globulin precursor

    See identical proteins and their annotated locations for NP_001009663.1

    Status: PROVISIONAL

    Source sequence(s)
    BC088300
    UniProtKB/Swiss-Prot
    P31211
    Related
    ENSRNOP00000012500.4, ENSRNOT00000012500.8
    Conserved Domains (1) summary
    cd02056
    Location:37392
    alpha-1-antitrypsin_like; alpha-1-antitrypsin_like. This family contains a variety of different members of clade A of the serpin superfamily. They include the classical serine proteinase inhibitors, alpha-1-antitrypsin and alpha-1-antichymotrypsin, protein C inhibitor, ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051341.1 Reference mRatBN7.2 Primary Assembly

    Range
    122780040..122790274 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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