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Snu13 small nuclear ribonucleoprotein 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 300092, updated on 13-Apr-2024

Summary

Official Symbol
Snu13provided by RGD
Official Full Name
small nuclear ribonucleoprotein 13provided by RGD
Primary source
RGD:1303103
See related
Ensembl:ENSRNOG00000006762 AllianceGenome:RGD:1303103
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Otk27; Nhp2l1
Summary
Predicted to enable ATPase binding activity and RNA binding activity. Predicted to contribute to snoRNA binding activity. Predicted to be involved in RNA processing and box C/D snoRNP assembly. Predicted to act upstream of or within single fertilization. Predicted to be located in dense fibrillar component. Predicted to be part of several cellular components, including U2-type precatalytic spliceosome; box C/D RNP complex; and spliceosomal snRNP complex. Orthologous to human SNU13 (small nuclear ribonucleoprotein 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 521.4), Spleen (RPKM 328.8) and 9 other tissues See more
Orthologs
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Genomic context

Location:
7q34
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (115445415..115451008, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (113565293..113570887, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (123282754..123287721, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103692950 Neighboring gene desumoylating isopeptidase 1 Neighboring gene X-ray repair cross complementing 6 Neighboring gene ATP synthase subunit a-like Neighboring gene hypothetical protein LOC100362109

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC72932

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATPase binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables U3 snoRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables U4 snRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables U4atac snRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables U4atac snRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables box C/D sno(s)RNA binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to snoRNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in box C/D snoRNP assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
involved_in mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within single fertilization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of U2-type precatalytic spliceosome ISO
Inferred from Sequence Orthology
more info
 
part_of U2-type precatalytic spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U4/U6 x U5 tri-snRNP complex ISO
Inferred from Sequence Orthology
more info
 
part_of U4/U6 x U5 tri-snRNP complex ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of U4atac snRNP ISO
Inferred from Sequence Orthology
more info
 
part_of U4atac snRNP ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of box C/D methylation guide snoRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of box C/D methylation guide snoRNP complex ISO
Inferred from Sequence Orthology
more info
 
located_in dense fibrillar component ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
 
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
NHP2-like protein 1
Names
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
U4/U6.U5 small nuclear ribonucleoprotein SNU13
U4/U6.U5 tri-snRNP 15.5 kDa protein
U4/U6.U5] tri-snRNP 15.5 kDa protein
high mobility group-like nuclear protein 2 homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212515.3NP_997680.1  NHP2-like protein 1

    See identical proteins and their annotated locations for NP_997680.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/Swiss-Prot
    P55770, Q6PDV0
    UniProtKB/TrEMBL
    A6HT43, A6HT44
    Related
    ENSRNOP00000009152.4, ENSRNOT00000009152.6
    Conserved Domains (1) summary
    cd21104
    Location:7128
    SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    115445415..115451008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)