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Hapstr1 HUWE1 associated protein modifying stress responses [ Rattus norvegicus (Norway rat) ]

Gene ID: 302913, updated on 5-Mar-2024

Summary

Official Symbol
Hapstr1provided by RGD
Official Full Name
HUWE1 associated protein modifying stress responsesprovided by RGD
Primary source
RGD:1309748
See related
Ensembl:ENSRNOG00000002545 AllianceGenome:RGD:1309748
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1309748
Summary
Orthologous to human C16orf72 (chromosome 16 open reading frame 72). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 261.8), Testes (RPKM 222.0) and 9 other tissues See more
Orthologs
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Genomic context

Location:
10q12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (7252737..7281678, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (6746037..6774992, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (6841071..6870011, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108352212 Neighboring gene uncharacterized LOC103693272 Neighboring gene uncharacterized LOC102546403 Neighboring gene ubiquitin specific peptidase 7 Neighboring gene cytochrome c oxidase subunit 6B1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
HUWE1-associated protein modifying stress responses 1
Names
UPF0472 protein C16orf72 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106972.1NP_001100442.1  HUWE1-associated protein modifying stress responses 1

    See identical proteins and their annotated locations for NP_001100442.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474017
    UniProtKB/TrEMBL
    A6K4L5, D3ZK25
    Related
    ENSRNOP00000003439.4, ENSRNOT00000003439.5
    Conserved Domains (1) summary
    pfam15251
    Location:25273
    DUF4588; Domain of unknown function (DUF4588)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    7252737..7281678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006245754.5XP_006245816.1  HUWE1-associated protein modifying stress responses 1 isoform X1

    See identical proteins and their annotated locations for XP_006245816.1

    UniProtKB/TrEMBL
    A6K4L5, D3ZK25
    Conserved Domains (1) summary
    pfam15251
    Location:25273
    DUF4588; Domain of unknown function (DUF4588)