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Maml1 mastermind-like transcriptional coactivator 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303101, updated on 30-Sep-2021

Summary

Official Symbol
Maml1provided by RGD
Official Full Name
mastermind-like transcriptional coactivator 1provided by RGD
Primary source
RGD:1308631
See related
EnsemblRapid:ENSRNOG00000003268
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Thymus (RPKM 44.8), Spleen (RPKM 39.5) and 9 other tissues See more
Orthologs
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Genomic context

See Maml1 in Genome Data Viewer
Location:
10q22
Exon count:
7
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (34588639..34624298, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (35765196..35801375, complement)

Chromosome 10 - NC_051345.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095091 Neighboring gene leukotriene C4 synthase Neighboring gene uncharacterized LOC120095092 Neighboring gene calnexin Neighboring gene chibby family member 3 Neighboring gene heterogeneous nuclear ribonucleoprotein H1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables peptide antigen binding ISO
Inferred from Sequence Orthology
more info
 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of MAML1-RBP-Jkappa- ICN1 complex ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mastermind-like protein 1
Names
mastermind like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106997.1NP_001100467.1  mastermind-like protein 1

    See identical proteins and their annotated locations for NP_001100467.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    D4A930

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051345.1 Reference mRatBN7.2 Primary Assembly

    Range
    34588639..34624298 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006246251.3XP_006246313.2  mastermind-like protein 1 isoform X1

    Related
    ENSRNOP00000004361.6, ENSRNOT00000004361.7
    Conserved Domains (2) summary
    pfam09596
    Location:1471
    MamL-1; MamL-1 domain
    pfam09770
    Location:368566
    PAT1; Topoisomerase II-associated protein PAT1
  2. XM_039085921.1XP_038941849.1  mastermind-like protein 1 isoform X2

  3. XM_039085920.1XP_038941848.1  mastermind-like protein 1 isoform X2

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