Cog1 component of oligomeric golgi complex 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cog1provided by RGD
Official Full Name: component of oligomeric golgi complex 1provided by RGD
Primary source: RGD:1304594
See related: Ensembl:ENSRNOG00000002795 AllianceGenome:RGD:1304594
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in intra-Golgi vesicle-mediated transport and protein transport. Predicted to be located in membrane. Predicted to be part of Golgi transport complex. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIg. Orthologous to human COG1 (component of oligomeric golgi complex 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Thymus (RPKM 104.3), Adrenal (RPKM 98.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q32.1

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (99192604..99207640)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (98695481..98708495)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (102167594..102180569)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH133716 (e-PCR)
- UniSTS:216999

RH127333 (e-PCR)
- UniSTS:210643

RH130214 (e-PCR)
- UniSTS:213501

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in Golgi organization	ISO Inferred from Sequence Orthology more info
involved_in glycosylation	ISO Inferred from Sequence Orthology more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in retrograde transport, vesicle recycling within Golgi	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
part_of Golgi transport complex	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: conserved oligomeric Golgi complex subunit 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107062.2 → NP_001100532.2 conserved oligomeric Golgi complex subunit 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000010

UniProtKB/TrEMBL

B5DFI1

Related

ENSRNOP00000091572.1, ENSRNOT00000113311.1

Conserved Domains (1) summary

pfam08700
Location:17 → 91

Vps51; Vps51/Vps67