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Abhd13 abhydrolase domain containing 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 306630, updated on 30-Mar-2024

Summary

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Official Symbol
Abhd13provided by RGD
Official Full Name
abhydrolase domain containing 13provided by RGD
Primary source
RGD:1308317
See related
Ensembl:ENSRNOG00000014598 AllianceGenome:RGD:1308317
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308317
Summary
Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be involved in protein depalmitoylation. Predicted to be located in dendrite cytoplasm. Predicted to be active in membrane. Orthologous to human ABHD13 (abhydrolase domain containing 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 93.9), Kidney (RPKM 85.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
16q12.5
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (86203851..86218843, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (79501879..79516712, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (85315275..85330108, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene myosin XVI Neighboring gene TNF superfamily member 13b Neighboring gene uncharacterized LOC120097573 Neighboring gene DNA ligase 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification of PSD-95 Depalmitoylating Enzymes. Yokoi N, et al. J Neurosci, 2016 Jun 15. PMID 27307232, Free PMC Article
  2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables palmitoyl-(protein) hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables palmitoyl-(protein) hydrolase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in macromolecule depalmitoylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in dendrite cytoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein ABHD13
Names
abhydrolase domain-containing protein 13
alpha/beta hydrolase domain-containing protein 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271072.1 → NP_001258001.1  protein ABHD13

    See identical proteins and their annotated locations for NP_001258001.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/TrEMBL
    A6IWS0, A6IWS1, D4A1B6
    Conserved Domains (2) summary
    pfam00561
    Location:115 → 300
    Abhydrolase_1; alpha/beta hydrolase fold
    pfam12695
    Location:116 → 299
    Abhydrolase_5; Alpha/beta hydrolase family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    86203851..86218843 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006253478.5 → XP_006253540.1  protein ABHD13 isoform X1

    See identical proteins and their annotated locations for XP_006253540.1

    UniProtKB/TrEMBL
    A6IWS0, A6IWS1, D4A1B6
    Related
    ENSRNOP00000084255.1
    Conserved Domains (2) summary
    pfam00561
    Location:115 → 300
    Abhydrolase_1; alpha/beta hydrolase fold
    pfam12695
    Location:116 → 299
    Abhydrolase_5; Alpha/beta hydrolase family

  2. XM_008771396.4 → XP_008769618.1  protein ABHD13 isoform X1

    See identical proteins and their annotated locations for XP_008769618.1

    UniProtKB/TrEMBL
    A6IWS0, A6IWS1, D4A1B6
    Related
    ENSRNOP00000079883.1
    Conserved Domains (2) summary
    pfam00561
    Location:115 → 300
    Abhydrolase_1; alpha/beta hydrolase fold
    pfam12695
    Location:116 → 299
    Abhydrolase_5; Alpha/beta hydrolase family

  3. XM_006253479.5 → XP_006253541.1  protein ABHD13 isoform X1

    See identical proteins and their annotated locations for XP_006253541.1

    UniProtKB/TrEMBL
    A6IWS0, A6IWS1, D4A1B6
    Related
    ENSRNOP00000019563.5
    Conserved Domains (2) summary
    pfam00561
    Location:115 → 300
    Abhydrolase_1; alpha/beta hydrolase fold
    pfam12695
    Location:116 → 299
    Abhydrolase_5; Alpha/beta hydrolase family

  4. XM_008771395.4 → XP_008769617.1  protein ABHD13 isoform X1

    See identical proteins and their annotated locations for XP_008769617.1

    UniProtKB/TrEMBL
    A6IWS0, A6IWS1, D4A1B6
    Conserved Domains (2) summary
    pfam00561
    Location:115 → 300
    Abhydrolase_1; alpha/beta hydrolase fold
    pfam12695
    Location:116 → 299
    Abhydrolase_5; Alpha/beta hydrolase family

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001107327.1: Suppressed sequence

    Description
    NM_001107327.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
Nucleotide Protein Strain
Heading Accession and Version

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