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Kdm2b lysine (K)-specific demethylase 2B [ Mus musculus (house mouse) ]

Gene ID: 30841, updated on 5-Sep-2021

Summary

Official Symbol
Kdm2bprovided by MGI
Official Full Name
lysine (K)-specific demethylase 2Bprovided by MGI
Primary source
MGI:MGI:1354737
See related
Ensembl:ENSMUSG00000029475
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cxxc2; Fbl10; Fbxl1; PCCX2; Fbxl10; Jhdm1b
Summary
The protein encoded by this gene is a H3K36-specific histone demethylase, which contains an N-terminal jumonji C domain, a CxxC zinc finger domain, a plant homeodomain finger, an F-box, and eight leucine-rich repeats. Amongst its demonstrated functions, this protein plays roles in the suppression of premature cellular senescence, leukemia maintenance and development, maintenance of mouse embryonic stem cell pluripotency, and induced pluripotent stem cell generation. Mice homozygous for a targeted deletion of the zinc finger domain display embryonic lethality with development ceasing at approximately 7 to 8 days post coitum, demonstrating an essential role in early development. A pseudogene of this gene is found on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Expression
Ubiquitous expression in CNS E14 (RPKM 10.9), whole brain E14.5 (RPKM 10.7) and 28 other tissues See more
Orthologs
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Genomic context

See Kdm2b in Genome Data Viewer
Location:
5; 5 F
Exon count:
30
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (123008727..123127333, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (122870664..122989270, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (123320677..123439101, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33044 Neighboring gene ring finger protein 34 Neighboring gene predicted gene, 33118 Neighboring gene RIKEN cDNA A930024E05 gene Neighboring gene predicted gene 2479

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA3014, E430001G17

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 
enables histone H3-di/monomethyl-lysine-36 demethylase activity IEA
Inferred from Electronic Annotation
more info
 
enables histone H3-methyl-lysine-36 demethylase activity ISO
Inferred from Sequence Orthology
more info
 
enables histone demethylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables histone demethylase activity TAS
Traceable Author Statement
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables unmethylated CpG binding ISO
Inferred from Sequence Orthology
more info
 
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in embryonic camera-type eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in forebrain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fourth ventricle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in hindbrain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in histone H2A monoubiquitination ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within histone H3-K36 demethylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in histone H3-K36 demethylation ISO
Inferred from Sequence Orthology
more info
 
involved_in initiation of neural tube closure IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in lateral ventricle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in midbrain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in midbrain-hindbrain boundary morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of neural precursor cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of cell growth IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of stem cell population maintenance IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein demethylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in third ventricle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of PcG protein complex ISO
Inferred from Sequence Orthology
more info
 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
lysine-specific demethylase 2B
Names
F-box and leucine-rich repeat protein 10
F-box protein FBL10
F-box protein containing leucine repeats 10
F-box/LRR-repeat protein 10
[Histone-H3]-lysine-36 demethylase 1B
jmjC domain-containing histone demethylation protein 1B
NP_001003953.1
NP_001365792.1
NP_001365793.1
NP_001365794.1
NP_038938.1
XP_006530439.1
XP_011246510.1
XP_011246511.1
XP_011246512.1
XP_011246513.1
XP_011246514.1
XP_011246515.1
XP_011246516.1
XP_011246517.1
XP_011246518.1
XP_036021058.1
XP_036021059.1
XP_036021060.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003953.2NP_001003953.1  lysine-specific demethylase 2B isoform 1

    See identical proteins and their annotated locations for NP_001003953.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK136625, BC065090
    Consensus CDS
    CCDS39259.1
    UniProtKB/Swiss-Prot
    Q6P1G2
    Related
    ENSMUSP00000038229.10, ENSMUST00000046073.16
    Conserved Domains (7) summary
    cd09293
    Location:10801280
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:151226
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    pfam02008
    Location:588624
    zf-CXXC; CXXC zinc finger domain
    sd00034
    Location:10751099
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:634695
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam12937
    Location:10411081
    F-box-like; F-box-like
    cl21464
    Location:198304
    cupin_like; Conserved domain found in cupin and related proteins
  2. NM_001378863.1NP_001365792.1  lysine-specific demethylase 2B isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC121564
    Related
    ENSMUSP00000083376.5, ENSMUST00000086200.11
    Conserved Domains (10) summary
    PTZ00449
    Location:687986
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:10741274
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:145220
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:10691093
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:628689
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:582618
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:10351073
    F-box-like
    pfam17811
    Location:297332
    JHD; Jumonji helical domain
    cl40423
    Location:192298
    cupin_RmlC-like; RmlC-like cupin superfamily
    cl40435
    Location:474540
    CTD_KDM2A_2B-like; C-terminal domain found in lysine-specific demethylase KDM2A, KDM2B, and similar proteins
  3. NM_001378864.1NP_001365793.1  lysine-specific demethylase 2B isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC121564
    Conserved Domains (6) summary
    PTZ00449
    Location:160462
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:561750
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:545569
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:101162
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:5591
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:511549
    F-box-like
  4. NM_001378865.1NP_001365794.1  lysine-specific demethylase 2B isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC121564
    Conserved Domains (5) summary
    cd09293
    Location:520709
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:504528
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:101162
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:5591
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:470508
    F-box-like
  5. NM_013910.2NP_038938.1  lysine-specific demethylase 2B isoform 2

    See identical proteins and their annotated locations for NP_038938.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks exons in the 5' UTR and 5' coding region and uses an alternate 5' terminal exon compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    BC057622, BC065090, BU841175
    Consensus CDS
    CCDS19657.1
    UniProtKB/Swiss-Prot
    Q6P1G2
    Related
    ENSMUSP00000031435.8, ENSMUST00000031435.14
    Conserved Domains (5) summary
    cd09293
    Location:558747
    AMN1; Antagonist of mitotic exit network protein 1
    pfam02008
    Location:5591
    zf-CXXC; CXXC zinc finger domain
    sd00034
    Location:542566
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:101162
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam12937
    Location:508548
    F-box-like; F-box-like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    123008727..123127333 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530376.4XP_006530439.1  lysine-specific demethylase 2B isoform X4

    Related
    ENSMUSP00000114052.3, ENSMUST00000118027.8
    Conserved Domains (9) summary
    cd09293
    Location:10421242
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:151226
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:10371061
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:634695
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:588624
    zf-CXXC; CXXC zinc finger domain
    pfam10477
    Location:718922
    EIF4E-T; Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E
    pfam12937
    Location:10031041
    F-box-like
    pfam17811
    Location:303338
    JHD; Jumonji helical domain
    cl21464
    Location:198297
    cupin_like; Conserved domain found in cupin and related proteins
  2. XM_011248210.3XP_011246512.1  lysine-specific demethylase 2B isoform X3

    Conserved Domains (9) summary
    cd09293
    Location:10451245
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:151226
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:10401064
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:634695
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:588624
    zf-CXXC; CXXC zinc finger domain
    pfam10477
    Location:721925
    EIF4E-T; Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E
    pfam12937
    Location:10061044
    F-box-like
    pfam17811
    Location:303338
    JHD; Jumonji helical domain
    cl21464
    Location:198297
    cupin_like; Conserved domain found in cupin and related proteins
  3. XM_011248208.3XP_011246510.1  lysine-specific demethylase 2B isoform X1

    Conserved Domains (9) summary
    PTZ00449
    Location:693995
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:10831283
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:151226
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:10781102
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:634695
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:588624
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:10441082
    F-box-like
    pfam17811
    Location:303338
    JHD; Jumonji helical domain
    cl21464
    Location:198297
    cupin_like; Conserved domain found in cupin and related proteins
  4. XM_011248212.4XP_011246514.1  lysine-specific demethylase 2B isoform X5

    See identical proteins and their annotated locations for XP_011246514.1

    Related
    ENSMUSP00000114049.2, ENSMUST00000121739.8
    Conserved Domains (9) summary
    PTZ00449
    Location:638940
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:10281228
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:96171
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:10231047
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:579640
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:533569
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:9891027
    F-box-like
    pfam17811
    Location:248283
    JHD; Jumonji helical domain
    cl21464
    Location:143242
    cupin_like; Conserved domain found in cupin and related proteins
  5. XM_011248211.4XP_011246513.1  lysine-specific demethylase 2B isoform X5

    See identical proteins and their annotated locations for XP_011246513.1

    Conserved Domains (9) summary
    PTZ00449
    Location:638940
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:10281228
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:96171
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:10231047
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:579640
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:533569
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:9891027
    F-box-like
    pfam17811
    Location:248283
    JHD; Jumonji helical domain
    cl21464
    Location:143242
    cupin_like; Conserved domain found in cupin and related proteins
  6. XM_011248209.4XP_011246511.1  lysine-specific demethylase 2B isoform X2

    Conserved Domains (9) summary
    PTZ00449
    Location:687989
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:10771277
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:145220
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:10721096
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:628689
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:582618
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:10381076
    F-box-like
    pfam17811
    Location:297332
    JHD; Jumonji helical domain
    cl21464
    Location:192291
    cupin_like; Conserved domain found in cupin and related proteins
  7. XM_011248215.2XP_011246517.1  lysine-specific demethylase 2B isoform X8

    Conserved Domains (9) summary
    PTZ00449
    Location:607909
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:9971197
    AMN1; Antagonist of mitotic exit network protein 1
    smart00558
    Location:65140
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    sd00034
    Location:9921016
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:548609
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:502538
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:958996
    F-box-like
    pfam17811
    Location:217252
    JHD; Jumonji helical domain
    cl21464
    Location:112211
    cupin_like; Conserved domain found in cupin and related proteins
  8. XM_036165165.1XP_036021058.1  lysine-specific demethylase 2B isoform X7

    Conserved Domains (9) summary
    PTZ00449
    Location:493792
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:8801080
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:875899
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:434495
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:388424
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:841879
    F-box-like
    pfam17811
    Location:103138
    JHD; Jumonji helical domain
    cd21785
    Location:280346
    CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
    cl40423
    Location:1104
    cupin_RmlC-like; RmlC-like cupin superfamily
  9. XM_011248214.3XP_011246516.1  lysine-specific demethylase 2B isoform X6

    See identical proteins and their annotated locations for XP_011246516.1

    Conserved Domains (8) summary
    PTZ00449
    Location:493795
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:8831083
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:878902
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:434495
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:388424
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:844882
    F-box-like
    pfam17811
    Location:103138
    JHD; Jumonji helical domain
    cl21464
    Location:197
    cupin_like; Conserved domain found in cupin and related proteins
  10. XM_011248213.4XP_011246515.1  lysine-specific demethylase 2B isoform X6

    See identical proteins and their annotated locations for XP_011246515.1

    Conserved Domains (8) summary
    PTZ00449
    Location:493795
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:8831083
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:878902
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:434495
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:388424
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:844882
    F-box-like
    pfam17811
    Location:103138
    JHD; Jumonji helical domain
    cl21464
    Location:197
    cupin_like; Conserved domain found in cupin and related proteins
  11. XM_011248216.3XP_011246518.1  lysine-specific demethylase 2B isoform X6

    See identical proteins and their annotated locations for XP_011246518.1

    Conserved Domains (8) summary
    PTZ00449
    Location:493795
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:8831083
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:878902
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:434495
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:388424
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:844882
    F-box-like
    pfam17811
    Location:103138
    JHD; Jumonji helical domain
    cl21464
    Location:197
    cupin_like; Conserved domain found in cupin and related proteins
  12. XM_036165167.1XP_036021060.1  lysine-specific demethylase 2B isoform X10

    Conserved Domains (7) summary
    PTZ00449
    Location:363662
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:750950
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:745769
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:304365
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:258294
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:711749
    F-box-like
    cd21785
    Location:150216
    CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B
  13. XM_036165166.1XP_036021059.1  lysine-specific demethylase 2B isoform X9

    Conserved Domains (7) summary
    PTZ00449
    Location:363665
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd09293
    Location:753953
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:748772
    LRR_AMN1; leucine-rich repeat [structural motif]
    cd15644
    Location:304365
    PHD_KDM2B; PHD finger found in Lysine-specific demethylase 2B (KDM2B)
    pfam02008
    Location:258294
    zf-CXXC; CXXC zinc finger domain
    pfam12937
    Location:714752
    F-box-like
    cd21785
    Location:150216
    CTD_KDM2B; C-terminal domain found in Lysine-specific demethylase 2B

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001005866.1: Suppressed sequence

    Description
    NM_001005866.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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