Peg12 paternally expressed 12 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Peg12provided by RGD
Official Full Name: paternally expressed 12provided by RGD
Primary source: RGD:1307664
See related: Ensembl:ENSRNOG00000024429 AllianceGenome:RGD:1307664
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in positive regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within embryonic axis specification. Predicted to be active in cytoplasm. Orthologous to human FRAT1 (FRAT regulator of WNT signaling pathway 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 1q22

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (125374399..125377002, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (115962511..115965114, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (123097861..123100464, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in positive regulation of canonical Wnt signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: paternally expressed 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001170562.1 → NP_001164033.1 paternally expressed 12

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

D3Z8R0

Related

ENSRNOP00000058978.1, ENSRNOT00000031973.4

Conserved Domains (1) summary

pfam05350
Location:1 → 233

GSK-3_bind; Glycogen synthase kinase-3 binding