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igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 [ Danio rerio (zebrafish) ]

Gene ID: 30967, updated on 14-Nov-2021

Summary

Official Symbol
igf2bp3provided by ZNC
Official Full Name
insulin-like growth factor 2 mRNA binding protein 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-000308-1
See related
Ensembl:ENSDARG00000010266
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
dvr1rbp; zVg1RBP; wu:fb79c12; wu:fe06h09
Orthologs
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Genomic context

See igf2bp3 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (20200134..20245496)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (20616654..20661378)
103 previous assembly Zv9 (GCF_000002035.4) 19 NC_007130.5 (20682384..20727793)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 126 Neighboring gene transformer 2 alpha homolog Neighboring gene glycoprotein (transmembrane) nmb Neighboring gene oxidoreductase NAD-binding domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mRNA 3'-UTR binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA 3'-UTR binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA transport IEA
Inferred from Electronic Annotation
more info
 
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of RNA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
insulin-like growth factor 2 mRNA-binding protein 3
Names
IGF-II mRNA-binding protein 3
IGF2 mRNA-binding protein 3
IMP-3
IMP3
VICKZ family member 3
Vg1 RBP
decapentaplegic and Vg-related 1 RNA-binding protein
vg1 RNA-binding protein
vg1-RBP

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131491.2NP_571566.1  insulin-like growth factor 2 mRNA-binding protein 3

    See identical proteins and their annotated locations for NP_571566.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045873
    UniProtKB/Swiss-Prot
    Q9PW80
    UniProtKB/TrEMBL
    B2GT58
    Related
    ENSDARP00000010878.6, ENSDART00000010140.7
    Conserved Domains (3) summary
    cd00105
    Location:278343
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd12627
    Location:177
    RRM1_IGF2BP3; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
    cd12630
    Location:81156
    RRM2_IGF2BP3; RNA recognition motif 2 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    20200134..20245496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009294198.3XP_009292473.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A0R4IYT0
    Related
    ENSDARP00000140941.1, ENSDART00000163026.2
    Conserved Domains (3) summary
    cd00105
    Location:278343
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd12627
    Location:177
    RRM1_IGF2BP3; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
    cd12630
    Location:81156
    RRM2_IGF2BP3; RNA recognition motif 2 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
  2. XM_021467992.1XP_021323667.1  insulin-like growth factor 2 mRNA-binding protein 3 isoform X2

    Conserved Domains (4) summary
    cd00105
    Location:278321
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd12627
    Location:177
    RRM1_IGF2BP3; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
    cd12630
    Location:81156
    RRM2_IGF2BP3; RNA recognition motif 2 in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
    pfam00013
    Location:197261
    KH_1; KH domain
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