U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG4293 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31001, updated on 10-May-2024

Summary

Go to the top of the page Help
Official Symbol
CG4293provided by FlyBase
Primary source
FLYBASE:FBgn0024983
Locus tag
Dmel_CG4293
See related
AllianceGenome:FB:FBgn0024983
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
154711_at; Dmel\CG4293; EG:65F1.1
Summary
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be active in COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum; and membrane. Is expressed in adult head; embryonic/larval salivary gland; embryonic/larval salivary gland body; organism; and salivary gland body primordium. Orthologous to human ERGIC2 (ERGIC and golgi 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG4293 in Genome Data Viewer
Location:
1B8-1B9; 1-0 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (527941..530291, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (421974..424324, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44892 Neighboring gene silver Neighboring gene elav noncoding regulatory RNA Neighboring gene embryonic lethal abnormal vision Neighboring gene arginase Neighboring gene beta amyloid protein precursor-like Neighboring gene mir-4960 stem loop Neighboring gene ventral nervous system defective Neighboring gene split discs

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genome wide ChIP-chip analyses reveal important roles for CTCF in Drosophila genome organization. Smith ST, et al. Dev Biol, 2009 Apr 15. PMID 19210964, Free PMC Article
  2. Microarray analysis of immune challenged Drosophila hemocytes. Johansson KC, et al. Exp Cell Res, 2005 Apr 15. PMID 15777795
  3. A comparative genomic analysis of two distant diptera, the fruit fly, Drosophila melanogaster, and the malaria mosquito, Anopheles gambiae. Bolshakov VN, et al. Genome Res, 2002 Jan. PMID 11779831, Free PMC Article
  4. The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. Pile LA, et al. J Biol Chem, 2003 Sep 26. PMID 12865422
  5. Genome-wide analysis on inbreeding effects on gene expression in Drosophila melanogaster. Kristensen TN, et al. Genetics, 2005 Sep. PMID 15944359, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in COPII-coated ER to Golgi transport vesicle ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG4293-PA
CG4293-PB
CG4293-PC
CG4293-PD
CG4293-PE

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    527941..530291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038727.1 → NP_001033816.1  uncharacterized protein Dmel_CG4293, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033816.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76896
    Conserved Domains (2) summary
    pfam07970
    Location:200 → 349
    COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    pfam13850
    Location:19 → 104
    ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

  2. NM_001038728.3 → NP_001033817.1  uncharacterized protein Dmel_CG4293, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033817.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76896
    Conserved Domains (2) summary
    pfam07970
    Location:200 → 349
    COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    pfam13850
    Location:19 → 104
    ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

  3. NM_001272170.1 → NP_001259099.1  uncharacterized protein Dmel_CG4293, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259099.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PGB8
    Conserved Domains (2) summary
    pfam07970
    Location:200 → 347
    COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    pfam13850
    Location:19 → 104
    ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

  4. NM_130491.5 → NP_569847.1  uncharacterized protein Dmel_CG4293, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_569847.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76896
    Related
    FBpp0070084
    Conserved Domains (2) summary
    pfam07970
    Location:200 → 349
    COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    pfam13850
    Location:19 → 104
    ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

  5. NM_166847.4 → NP_726677.1  uncharacterized protein Dmel_CG4293, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726677.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76896
    Related
    FBpp0070085
    Conserved Domains (2) summary
    pfam07970
    Location:200 → 349
    COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
    pfam13850
    Location:19 → 104
    ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PGB8 M9PGB8
O76896 O76896

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools