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usp ultraspiracle [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31165, updated on 11-Jun-2019

Summary

Official Symbol
uspprovided by FlyBase
Official Full Name
ultraspiracleprovided by FlyBase
Primary source
FLYBASE:FBgn0003964
Locus tag
Dmel_CG4380
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
2C; cf1; Cf1; CF1; CF1/Usp; CF1/USP; CG4380; Dmel\CG4380; dmUSP; DmUsp; DmUSP; dUSP; EG:22E5.1; l(1)2Cf; l(1)usp; NR2B4; Usp; USP; XR2C

Genomic context

See usp in Genome Data Viewer
Location:
2C7-2C7; 1-0.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2038798..2042311, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1932831..1936344, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene enhanced adult sensory threshold Neighboring gene alpha actinin Neighboring gene mir-4954 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene moody

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to DNA-binding transcription activator activity, RNA polymerase II-specific IPI
Inferred from Physical Interaction
more info
PubMed 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to ecdysone binding IDA
Inferred from Direct Assay
more info
PubMed 
hormone binding IDA
Inferred from Direct Assay
more info
PubMed 
lipid binding IDA
Inferred from Direct Assay
more info
PubMed 
nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to nuclear receptor activity IPI
Inferred from Physical Interaction
more info
PubMed 
nuclear receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
steroid hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 
transcription regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
anatomical structure development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
border follicle cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to ecdysone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to ecdysone IDA
Inferred from Direct Assay
more info
PubMed 
dendrite morphogenesis NAS
Non-traceable Author Statement
more info
PubMed 
ecdysone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
germ cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
metamorphosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
mushroom body development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell differentiation TAS
Traceable Author Statement
more info
PubMed 
negative regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
neuron remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
pupariation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of development, heterochronic TAS
Traceable Author Statement
more info
PubMed 
regulation of organ growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to ecdysone IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to starvation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
RNA polymerase II transcription factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
activator ecdysone receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
activator ecdysone receptor complex IDA
Inferred from Direct Assay
more info
PubMed 
dendrite IMP
Inferred from Mutant Phenotype
more info
PubMed 
ecdysone receptor holocomplex IPI
Inferred from Physical Interaction
more info
PubMed 
ecdysone receptor holocomplex TAS
Traceable Author Statement
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
polytene chromosome NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
ultraspiracle
Names
CG4380-PA
CG4380-PB
X receptor at 2C
chorion factor 1
chorion factor CF1
ultraspiricle
usp-PA
usp-PB

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2038798..2042311 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272239.2NP_001259168.1  ultraspiracle, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259168.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P20153
    UniProtKB/TrEMBL
    M9PGS2
    Related
    FBpp0305937, FBtr0333803
    Conserved Domains (2) summary
    cd06943
    Location:237480
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:102178
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
  2. NM_057433.4NP_476781.1  ultraspiracle, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476781.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P20153
    UniProtKB/TrEMBL
    M9PGS2
    Related
    FBpp0070332, FBtr0070346
    Conserved Domains (2) summary
    cd06943
    Location:237480
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:102178
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
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