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CG4313 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31169, updated on 4-Apr-2024

Summary

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Official Symbol
CG4313provided by FlyBase
Primary source
FLYBASE:FBgn0025632
Locus tag
Dmel_CG4313
See related
AllianceGenome:FB:FBgn0025632
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG 4313; Dmel\CG4313; Dmel_CG4313; EG:22E5.10
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be integral component of membrane. Is expressed in embryonic/larval visceral muscle cell and organism. Orthologous to human GPR84 (G protein-coupled receptor 84). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
2C7-2C8; 1-0.5 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2041868..2055414)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1935901..1949447)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene enhanced adult sensory threshold Neighboring gene alpha actinin Neighboring gene mir-4954 stem loop Neighboring gene ultraspiracle Neighboring gene uncharacterized protein Neighboring gene moody Neighboring gene antisense RNA:CR44896 Neighboring gene Salt-inducible kinase 2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Investigation of Evolutionary History and Origin of the Tre1 Family Suggests a Role in Regulating Hemocytes Cells Infiltration of the Blood-Brain Barrier. Kubick N, et al. Insects, 2021 Sep 29. PMID 34680651, Free PMC Article
  2. Melatonin increases the regularity of cardiac rhythmicity in the Drosophila heart in both wild-type and strains bearing pathogenic mutations. VanKirk T, et al. J Comp Physiol B, 2017 Jan. PMID 27448293
  3. moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila. Bainton RJ, et al. Cell, 2005 Oct 7. PMID 16213219
  4. Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells. Kunwar PS, et al. PLoS Biol, 2003 Dec. PMID 14691551, Free PMC Article
  5. Extensive crosstalk of G protein-coupled receptors with the Hedgehog signalling pathway. Saad F, et al. Development, 2021 Apr 1. PMID 33653875, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables G protein-coupled receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG4313-PC
CG4313-PD
CG4313-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2041868..2055414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001297871.1 → NP_001284800.1  uncharacterized protein Dmel_CG4313, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284800.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9K8
    Conserved Domains (1) summary
    cl21561
    Location:248 → 315
    7tm_4; Olfactory receptor

  2. NM_001297870.1 → NP_001284799.1  uncharacterized protein Dmel_CG4313, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284799.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9K8
    Conserved Domains (1) summary
    cl21561
    Location:248 → 315
    7tm_4; Olfactory receptor

  3. NM_130615.3 → NP_569971.3  uncharacterized protein Dmel_CG4313, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_569971.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    O77269, Q9W533
    Conserved Domains (1) summary
    cd15210
    Location:78 → 505
    7tmA_GPR84-like; G protein-coupled receptor 84 and similar proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O77269 O77269
Q8T9K8 Q8T9K8
Q9W533 Q9W533

Gene LinkOut

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