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Ddx41 DEAD-box helicase 41 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314336, updated on 22-Aug-2021

Summary

Symbol
Ddx41provided by RGD
Full Name
DEAD-box helicase 41provided by RGD
Primary source
RGD:1311758
See related
Ensembl:ENSRNOG00000012771
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Kidney (RPKM 127.7), Thymus (RPKM 114.2) and 9 other tissues See more
Orthologs
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Genomic context

See Ddx41 in Genome Data Viewer
Location:
17p14
Exon count:
18
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (9102926..9108415)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (9631925..9637317)

Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene transmembrane p24 trafficking protein 9 Neighboring gene family with sequence similarity 193, member B Neighboring gene uncharacterized LOC108348505 Neighboring gene microRNA 3542 Neighboring gene docking protein 3 Neighboring gene PDZ and LIM domain 7

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
probable ATP-dependent RNA helicase DDX41
Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
probable ATP-dependent RNA helicase DDX41-like
NP_001101516.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108046.2NP_001101516.1  probable ATP-dependent RNA helicase DDX41

    See identical proteins and their annotated locations for NP_001101516.1

    Status: PROVISIONAL

    Source sequence(s)
    BC166825
    UniProtKB/TrEMBL
    B2RYL8
    Related
    ENSRNOP00000018114.5, ENSRNOT00000018114.5
    Conserved Domains (3) summary
    smart00487
    Location:196409
    DEXDc; DEAD-like helicases superfamily
    cd00268
    Location:183397
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam00271
    Location:418527
    Helicase_C; Helicase conserved C-terminal domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

    Range
    9102926..9108415
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_005495290.1 RNA Sequence

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