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CG3149 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31489, updated on 10-May-2024

Summary

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Official Symbol
CG3149provided by FlyBase
Primary source
FLYBASE:FBgn0027564
Locus tag
Dmel_CG3149
See related
AllianceGenome:FB:FBgn0027564
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH08388; Dmel\CG3149
Summary
Predicted to be involved in glycolipid translocation. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation In. Orthologous to human RFT1 (RFT1 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG3149 in Genome Data Viewer
Location:
5A13-5A14; 1-12 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5692945..5695205, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5586978..5589238, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Post-GPI attachment to proteins 1 Neighboring gene antisense RNA:CR45525 Neighboring gene crossveinless Neighboring gene long non-coding RNA:CR42794 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif B Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. crossveinless defines a new family of Twisted-gastrulation-like modulators of bone morphogenetic protein signalling. Vilmos P, et al. EMBO Rep, 2005 Mar. PMID 15711536, Free PMC Article
  2. The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing. Shimmi O, et al. Dev Biol, 2005 Jun 1. PMID 15936330
  3. Genomic organization of gypsy chromatin insulators in Drosophila melanogaster. Ramos E, et al. Genetics, 2006 Apr. PMID 16452134, Free PMC Article
  4. A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila. Okamoto N, et al. Dev Cell, 2018 Nov 5. PMID 30293839, Free PMC Article
  5. A Genetic Screen for Genes That Impact Peroxisomes in Drosophila Identifies Candidate Genes for Human Disease. Graves HK, et al. G3 (Bethesda), 2020 Jan 7. PMID 31767637, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in dolichol-linked oligosaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glycolipid translocation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3149-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    5692945..5695205 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132018.3 → NP_572246.1  uncharacterized protein Dmel_CG3149 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572246.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9Y123
    Related
    FBpp0070811
    Conserved Domains (1) summary
    pfam04506
    Location:8 → 547
    Rft-1; Rft protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Y123.1 Q9Y123

Gene LinkOut

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