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Josd1 Josephin domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 315134, updated on 5-Mar-2024

Summary

Official Symbol
Josd1provided by RGD
Official Full Name
Josephin domain containing 1provided by RGD
Primary source
RGD:1305388
See related
Ensembl:ENSRNOG00000014440 AllianceGenome:RGD:1305388
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305388
Summary
Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Predicted to be located in cytoplasm and plasma membrane. Orthologous to human JOSD1 (Josephin domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 129.2), Kidney (RPKM 114.6) and 9 other tissues See more
Orthologs
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Genomic context

See Josd1 in Genome Data Viewer
Location:
7q34
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (113110709..113124632, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (111230318..111244241, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (120905343..120919261, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479938 Neighboring gene chibby 1, beta catenin antagonist Neighboring gene translocase of outer mitochondrial membrane 22 Neighboring gene GTP binding protein 1 Neighboring gene Sad1 and UNC84 domain containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC109161

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in protein deubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
josephin-1
Names
josephin domain-containing protein 1
NP_001020180.1
XP_038935196.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025009.1NP_001020180.1  josephin-1

    See identical proteins and their annotated locations for NP_001020180.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091280
    UniProtKB/Swiss-Prot
    Q5BJY4
    UniProtKB/TrEMBL
    A6HST3
    Related
    ENSRNOP00000019612.4, ENSRNOT00000019612.7
    Conserved Domains (1) summary
    pfam02099
    Location:31173
    Josephin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    113110709..113124632 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079268.2XP_038935196.1  josephin-1 isoform X1

    Conserved Domains (1) summary
    pfam02099
    Location:31103
    Josephin