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Fam81a family with sequence similarity 81, member A [ Rattus norvegicus (Norway rat) ]

Gene ID: 315789, updated on 5-Mar-2024

Summary

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Official Symbol
Fam81aprovided by RGD
Official Full Name
family with sequence similarity 81, member Aprovided by RGD
Primary source
RGD:1311958
See related
Ensembl:ENSRNOG00000057501 AllianceGenome:RGD:1311958
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311958
Summary
Orthologous to human FAM81A (family with sequence similarity 81 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 208.1), Kidney (RPKM 195.2) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
8q24
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (79643754..79702792, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (70762852..70821898, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (76521662..76579387, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene glucosaminyl (N-acetyl) transferase 3, mucin type Neighboring gene selenoprotein K, pseudogene 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC134480071

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. FAM81A protein, a novel component of the postsynaptic density in adult brain. Dosemeci A, et al. Neurosci Lett, 2019 Apr 23. PMID 30735723, Free PMC Article
  2. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in postsynaptic density, intracellular component IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein FAM81A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108163.1 → NP_001101633.1  protein FAM81A

    See identical proteins and their annotated locations for NP_001101633.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474041
    UniProtKB/TrEMBL
    A6KEU1, D4A7T8
    Related
    ENSRNOP00000071796.1, ENSRNOT00000090747.2
    Conserved Domains (1) summary
    COG1196
    Location:76 → 317
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    79643754..79702792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006243379.5 → XP_006243441.1  protein FAM81A isoform X1

    See identical proteins and their annotated locations for XP_006243441.1

    UniProtKB/TrEMBL
    A6KEU1, D4A7T8
    Conserved Domains (1) summary
    COG1196
    Location:76 → 317
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_006243378.5 → XP_006243440.1  protein FAM81A isoform X1

    See identical proteins and their annotated locations for XP_006243440.1

    UniProtKB/TrEMBL
    A6KEU1, D4A7T8
    Conserved Domains (1) summary
    COG1196
    Location:76 → 317
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein Strain
Heading Accession and Version

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