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MYH10 myosin heavy chain 10 [ Bos taurus (cattle) ]

Gene ID: 317655, updated on 8-Jul-2021

Summary

Official Symbol
MYH10provided by VGNC
Official Full Name
myosin heavy chain 10provided by VGNC
Primary source
VGNC:VGNC:31794
See related
BGD:BT23905; Ensembl:ENSBTAG00000021151
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See MYH10 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
43
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 19 NC_037346.1 (28061491..28183071, complement)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 19 AC_000176.1 (28679649..28801223, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2 B pseudogene Neighboring gene nudE neurodevelopment protein 1 like 1 Neighboring gene ring finger protein 222 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene U6 spliceosomal RNA Neighboring gene coiled-coil domain containing 42

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA stem-loop binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
 
enables microfilament motor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in actin filament-based movement IEA
Inferred from Electronic Annotation
more info
 
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of protein secretion IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 
located_in cleavage furrow IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
 
located_in midbody IEA
Inferred from Electronic Annotation
more info
 
part_of myosin II complex IEA
Inferred from Electronic Annotation
more info
 
located_in myosin II filament IEA
Inferred from Electronic Annotation
more info
 
part_of polysome IEA
Inferred from Electronic Annotation
more info
 
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
myosin-10
Names
NMMHC II-b
NMMHC-B
NMMHC-IIB
cellular myosin heavy chain, type B
myosin heavy chain, non-muscle IIb
myosin, heavy polypeptide 10, non-muscle
non-muscle myosin heavy chain B
non-muscle myosin heavy chain IIb
nonmuscle myosin heavy chain B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174834.1NP_777259.1  myosin-10

    See identical proteins and their annotated locations for NP_777259.1

    Status: PROVISIONAL

    Source sequence(s)
    AB022023
    UniProtKB/Swiss-Prot
    Q27991
    Related
    ENSBTAP00000065840.1, ENSBTAT00000075528.1
    Conserved Domains (8) summary
    cd14920
    Location:99771
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87771
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:8481928
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:3472
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:10621093
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:11111222
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:16451696
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:17691867
    DUF2570; Protein of unknown function (DUF2570)

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    28061491..28183071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005220299.4XP_005220356.1  myosin-10 isoform X2

    Conserved Domains (8) summary
    cd14920
    Location:99792
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87792
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:8691949
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:3472
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:10831114
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:11321243
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:16661717
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:17901888
    DUF2570; Protein of unknown function (DUF2570)
  2. XM_005220297.4XP_005220354.1  myosin-10 isoform X1

    See identical proteins and their annotated locations for XP_005220354.1

    Conserved Domains (8) summary
    cd14920
    Location:99802
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87802
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:8791959
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:3472
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:10931124
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:11421253
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:16761727
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:18001898
    DUF2570; Protein of unknown function (DUF2570)
  3. XM_015458671.2XP_015314157.1  myosin-10 isoform X3

    Conserved Domains (8) summary
    cd14920
    Location:99781
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87781
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:8581938
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:3472
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:10721103
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:11211232
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:16551706
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:17791877
    DUF2570; Protein of unknown function (DUF2570)
  4. XM_005220298.4XP_005220355.1  myosin-10 isoform X1

    See identical proteins and their annotated locations for XP_005220355.1

    Conserved Domains (8) summary
    cd14920
    Location:99802
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87802
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:8791959
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:3472
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:10931124
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:11421253
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:16761727
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:18001898
    DUF2570; Protein of unknown function (DUF2570)
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