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Gimap5 GTPase, IMAP family member 5 [ Mus musculus (house mouse) ]

Gene ID: 317757, updated on 17-Oct-2021

Summary

Official Symbol
Gimap5provided by MGI
Official Full Name
GTPase, IMAP family member 5provided by MGI
Primary source
MGI:MGI:2442232
See related
Ensembl:ENSMUSG00000043505
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D630024P16; E230026N22Rik
Summary
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Expression
Biased expression in spleen adult (RPKM 18.2), lung adult (RPKM 6.7) and 13 other tissues See more
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Genomic context

See Gimap5 in Genome Data Viewer
Location:
6; 6 B2.3
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (48723131..48731134)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (48746197..48754200)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (48696196..48704199)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene GTPase, IMAP family member 7 Neighboring gene GTPase, IMAP family member 1 Neighboring gene GTPase, IMAP family member 3 Neighboring gene predicted gene, 30714

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in T cell homeostasis ISO
Inferred from Sequence Orthology
more info
 
involved_in myeloid dendritic cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of T cell activation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of interferon-gamma production ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of lipid catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of nitric oxide biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of calcium ion transport into cytosol ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gamma-delta T cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of humoral immune response mediated by circulating immunoglobulin ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of membrane potential ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of natural killer cell cytokine production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of natural killer cell mediated cytotoxicity ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of mitochondrial membrane permeability ISO
Inferred from Sequence Orthology
more info
 
involved_in temperature homeostasis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
GTPase IMAP family member 5
Names
GTPase of the immunity-associated protein 5
immunity-associated nucleotide 4-like 1 protein
immunity-associated protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175035.5NP_778200.1  GTPase IMAP family member 5

    See identical proteins and their annotated locations for NP_778200.1

    Status: REVIEWED

    Source sequence(s)
    AC115045, AC153894
    Consensus CDS
    CCDS20114.1
    UniProtKB/Swiss-Prot
    Q8BWF2
    Related
    ENSMUSP00000056820.6, ENSMUST00000055558.6
    Conserved Domains (1) summary
    pfam04548
    Location:27227
    AIG1; AIG1 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    48723131..48731134
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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