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H2ac24 H2A clustered histone 24 [ Mus musculus (house mouse) ]

Gene ID: 319171, updated on 5-Sep-2021

Summary

Official Symbol
H2ac24provided by MGI
Official Full Name
H2A clustered histone 24provided by MGI
Primary source
MGI:MGI:3710573
See related
Ensembl:ENSMUSG00000094777
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hist1; Gm11276; Hist1h2ap
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Sep 2015]
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Genomic context

See H2ac24 in Genome Data Viewer
Location:
13; 13 A3.1
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (22017194..22017645, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (21833024..21833475, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (21924952..21925344, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53778 Neighboring gene H4 clustered histone 18 Neighboring gene H2B clustered histone 24 Neighboring gene nuclear encoded tRNA leucine 2 (anticodon TAA)

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the H2ac24 gene: The H2ac24 gene is conserved in dog, cow, rat, zebrafish, fruit fly, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, and rice.
  • Orthologs

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
histone H2A type 1-P
Names
Histone H2A type 1-O
Histone H2A type 1-P
histone H2A type 1
histone cluster 1, H2ap

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178185.2NP_835492.1  histone H2A type 1-P

    See identical proteins and their annotated locations for NP_835492.1

    Status: REVIEWED

    Source sequence(s)
    AL589879
    Consensus CDS
    CCDS26301.1
    UniProtKB/Swiss-Prot
    C0HKE1, C0HKE2, C0HKE3, C0HKE4, C0HKE5, C0HKE6, C0HKE7, C0HKE8, C0HKE9
    UniProtKB/TrEMBL
    B2RVF0
    Related
    ENSMUSP00000080088.6, ENSMUST00000081342.7
    Conserved Domains (1) summary
    PTZ00017
    Location:1130
    PTZ00017; histone H2A; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    22017194..22017645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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