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Ablim3 actin binding LIM protein family, member 3 [ Mus musculus (house mouse) ]

Gene ID: 319713, updated on 5-Sep-2021

Summary

Official Symbol
Ablim3provided by MGI
Official Full Name
actin binding LIM protein family, member 3provided by MGI
Primary source
MGI:MGI:2442582
See related
Ensembl:ENSMUSG00000032735
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AW990719; D930036B08Rik
Expression
Broad expression in subcutaneous fat pad adult (RPKM 16.1), CNS E18 (RPKM 14.9) and 17 other tissues See more
Orthologs
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Genomic context

See Ablim3 in Genome Data Viewer
Location:
18; 18 E1
Exon count:
26
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (61932463..62044956, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (61799392..61911885, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (61959046..62071506, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1500015A07 gene Neighboring gene GrpE-like 2, mitochondrial Neighboring gene actin filament associated protein 1-like 1 Neighboring gene predicted gene, 41748 Neighboring gene predicted gene, 35919 Neighboring gene predicted gene, 35720 Neighboring gene SH3 domain and tetratricopeptide repeats 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0843, MGC69876

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within cilium assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
involved_in lamellipodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within lamellipodium assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in lamellipodium ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in stress fiber IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in stress fiber ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
actin-binding LIM protein 3
Names
abLIM-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164491.1NP_001157963.1  actin-binding LIM protein 3 isoform 1

    See identical proteins and their annotated locations for NP_001157963.1

    Status: VALIDATED

    Source sequence(s)
    AC091677, BC060275, CF171696
    Consensus CDS
    CCDS37839.1
    UniProtKB/Swiss-Prot
    Q69ZX8
    Related
    ENSMUSP00000125836.2, ENSMUST00000166783.3
    Conserved Domains (6) summary
    smart00153
    Location:647682
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273645
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  2. NM_001360868.1NP_001347797.1  actin-binding LIM protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC091677, AC125157
    Conserved Domains (6) summary
    smart00153
    Location:614649
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273612
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  3. NM_198649.3NP_941051.2  actin-binding LIM protein 3 isoform 1

    See identical proteins and their annotated locations for NP_941051.2

    Status: VALIDATED

    Source sequence(s)
    AC091677, BC094229
    Consensus CDS
    CCDS37839.1
    UniProtKB/Swiss-Prot
    Q69ZX8
    Related
    ENSMUSP00000041243.9, ENSMUST00000049378.15
    Conserved Domains (6) summary
    smart00153
    Location:647682
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273645
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    61932463..62044956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030250507.2XP_030106367.1  actin-binding LIM protein 3 isoform X7

    Conserved Domains (6) summary
    smart00153
    Location:536571
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273534
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  2. XM_030250506.1XP_030106366.1  actin-binding LIM protein 3 isoform X4

    Conserved Domains (6) summary
    smart00153
    Location:598633
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273596
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  3. XM_036161169.1XP_036017062.1  actin-binding LIM protein 3 isoform X2

    Conserved Domains (6) summary
    smart00153
    Location:631666
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273630
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  4. XM_006526006.5XP_006526069.1  actin-binding LIM protein 3 isoform X2

    Conserved Domains (6) summary
    smart00153
    Location:631666
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273630
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  5. XM_006526005.5XP_006526068.1  actin-binding LIM protein 3 isoform X1

    Conserved Domains (6) summary
    smart00153
    Location:637672
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273635
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  6. XM_006526010.5XP_006526073.1  actin-binding LIM protein 3 isoform X6

    Conserved Domains (6) summary
    smart00153
    Location:552587
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273550
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  7. XM_006526009.5XP_006526072.1  actin-binding LIM protein 3 isoform X5

    Conserved Domains (6) summary
    smart00153
    Location:585620
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273583
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  8. XM_006526008.5XP_006526071.1  actin-binding LIM protein 3 isoform X4

    Conserved Domains (6) summary
    smart00153
    Location:598633
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273596
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  9. XM_006526007.5XP_006526070.1  actin-binding LIM protein 3 isoform X3

    Conserved Domains (6) summary
    smart00153
    Location:614649
    VHP; Villin headpiece domain
    cd09327
    Location:2374
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:79134
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:151202
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:210265
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:273612
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  10. XM_030250508.1XP_030106368.1  actin-binding LIM protein 3 isoform X8

    Conserved Domains (4) summary
    smart00153
    Location:511546
    VHP; Villin headpiece domain
    cd09329
    Location:1566
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:74129
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:137509
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  11. XM_006526012.2XP_006526075.1  actin-binding LIM protein 3 isoform X9

    Conserved Domains (3) summary
    smart00153
    Location:408443
    VHP; Villin headpiece domain
    cl02475
    Location:1226
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:34406
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
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