Abi3bp ABI family member 3 binding protein [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Abi3bpprovided by MGI
Official Full Name: ABI family member 3 binding proteinprovided by MGI
Primary source: MGI:MGI:2444583
See related: Ensembl:ENSMUSG00000035258 AllianceGenome:MGI:2444583
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: TARSH; eratin; 5033411B22Rik; D930038M13Rik
Summary: Enables collagen binding activity and heparin binding activity. Involved in negative regulation of cell population proliferation; negative regulation of connective tissue replacement involved in inflammatory response wound healing; and positive regulation of cardiocyte differentiation. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in interstitial matrix. Is expressed in several structures, including connective tissue; gut; male reproductive gland or organ; olfactory epithelium; and quadriceps femoris muscle. Orthologous to human ABI3BP (ABI family member 3 binding protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in bladder adult (RPKM 9.2), limb E14.5 (RPKM 7.8) and 16 other tissues See more
Orthologs: human all
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Genomic context

Location:: 16 C1.1; 16 34.09 cM

Exon count:: 64

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (56298179..56510498)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (56477801..56690135)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This is the first report of susceptibility to cigarette smoke-induced emphysema in 34 inbred strains of mice, and Abi3bp is identified as a potential contributor to this phenotype.
Title: Variable Susceptibility to Cigarette Smoke-Induced Emphysema in 34 Inbred Strains of Mice Implicates Abi3bp in Emphysema Susceptibility.
Constructed an Abi3bp-deficient mouse model and observed phenotypic changes. The generated Abi3bp-knockout mice are viable and fertile, develop normally and exhibit no significant differences in anxiety or depression-like behaviors, olfactory function and tumor incidence.
Title: Knockout of Abi3bp in mice does not affect their olfactory function, mental state and NNK-induced lung tumorigenesis.
Identified Abi3bp as a protein important for cardiac progenitor cell differentiation and proliferation.
Title: Abi3bp regulates cardiac progenitor cell proliferation and differentiation.
Abi3bp knockout increased MSC number and proliferation in bone marrow, lung, and liver.
Title: Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biology.
a p53-dependent apoptosis function of the mouse TARSH gene.
Title: A novel p53-dependent apoptosis function of TARSH in tumor development.
NESH (Abi-3), like Abi-1 and Abi-2, is a component of the Abi/WAVE complex, but likely plays a different role in the regulation of c-Abl.
Title: NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (6) 1 citation
Endonuclease-mediated (2)

General gene information

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Markers

AA926352 (e-PCR)
- UniSTS:261896

D16Ium65 (e-PCR), detects polymorphism
- UniSTS:142064

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables actin filament binding	ISO Inferred from Sequence Orthology more info
enables collagen binding	IDA Inferred from Direct Assay more info	PubMed
enables extracellular matrix structural constituent	RCA inferred from Reviewed Computational Analysis more info	PubMed
enables glycosaminoglycan binding	IDA Inferred from Direct Assay more info	PubMed
enables heparin binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	ISO Inferred from Sequence Orthology more info
involved_in extracellular matrix organization	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within extracellular matrix organization	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of cell population proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of connective tissue replacement involved in inflammatory response wound healing	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of cardiocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of cell-substrate adhesion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of cell-substrate adhesion	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of dendritic spine morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in regulation of postsynaptic density assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in collagen-containing extracellular matrix	HDA more info	PubMed
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
located_in dendritic shaft	ISO Inferred from Sequence Orthology more info
located_in dendritic spine	ISO Inferred from Sequence Orthology more info
located_in extracellular matrix	IDA Inferred from Direct Assay more info	PubMed
located_in interstitial matrix	IDA Inferred from Direct Assay more info	PubMed
located_in lamellipodium	ISO Inferred from Sequence Orthology more info
located_in postsynaptic density	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: target of Nesh-SH3

Names: ABI gene family, member 3 (NESH) binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001014399.3 → NP_001014421.2 target of Nesh-SH3 isoform 3 precursor

Status: VALIDATED

Source sequence(s)

AC117201, CT025158

Consensus CDS

CCDS37362.1

UniProtKB/TrEMBL

E9Q8E3, Q59IW8

Related

ENSMUSP00000128818.2, ENSMUST00000171000.3

Conserved Domains (2) summary

cd00063
Location:673 → 764

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 204

fn3; Fibronectin type III domain
NM_001014422.3 → NP_001014422.1 target of Nesh-SH3 isoform 4 precursor

See identical proteins and their annotated locations for NP_001014422.1

Status: VALIDATED

Source sequence(s)

AC117201, CT025158

Consensus CDS

CCDS88945.1

UniProtKB/TrEMBL

Q59IW7, Q59IW8

Related

ENSMUSP00000156180.2, ENSMUST00000231870.2

Conserved Domains (2) summary

cd00063
Location:863 → 954

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 204

fn3; Fibronectin type III domain
NM_001014423.3 → NP_001014423.1 target of Nesh-SH3 isoform 5 precursor

See identical proteins and their annotated locations for NP_001014423.1

Status: VALIDATED

Source sequence(s)

AC117201, CT025158

Consensus CDS

CCDS37359.1

UniProtKB/TrEMBL

Q59IW6

Related

ENSMUSP00000036257.8, ENSMUST00000048471.15

Conserved Domains (2) summary

cd00063
Location:943 → 1034

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 204

fn3; Fibronectin type III domain
NM_001014424.3 → NP_001014424.1 target of Nesh-SH3 isoform 2 precursor

See identical proteins and their annotated locations for NP_001014424.1

Status: VALIDATED

Source sequence(s)

AC117201, CT025158

Consensus CDS

CCDS37360.1

UniProtKB/TrEMBL

Q59IW5, Q59IW8

Related

ENSMUSP00000093712.4, ENSMUST00000096013.11

Conserved Domains (2) summary

cd00063
Location:879 → 970

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 204

fn3; Fibronectin type III domain
NM_178790.5 → NP_848905.2 target of Nesh-SH3 isoform 1 precursor

See identical proteins and their annotated locations for NP_848905.2

Status: VALIDATED

Source sequence(s)

AC117201, CT025158

Consensus CDS

CCDS37361.1

UniProtKB/TrEMBL

Q59IW8, Q59IW9

Related

ENSMUSP00000093711.4, ENSMUST00000096012.11

Conserved Domains (2) summary

cd00063
Location:843 → 934

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 204

fn3; Fibronectin type III domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000082.7 Reference GRCm39 C57BL/6J

Range

56298179..56510498

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_036159995.1 → XP_036015888.1 target of Nesh-SH3 isoform X35

Conserved Domains (3) summary

PHA03247
Location:507 → 893

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1446 → 1537

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 195

fn3; Fibronectin type III domain
XM_006522251.2 → XP_006522314.1 target of Nesh-SH3 isoform X1

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1402 → 1493

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522254.3 → XP_006522317.1 target of Nesh-SH3 isoform X5

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1386 → 1477

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522261.3 → XP_006522324.1 target of Nesh-SH3 isoform X12

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1366 → 1457

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_036159993.1 → XP_036015886.1 target of Nesh-SH3 isoform X24

Conserved Domains (5) summary

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PHA03307
Location:943 → 1197

PHA03307; transcriptional regulator ICP4; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1313 → 1404

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 195

fn3; Fibronectin type III domain
XM_006522257.4 → XP_006522320.1 target of Nesh-SH3 isoform X8

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1378 → 1469

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522267.4 → XP_006522330.1 target of Nesh-SH3 isoform X20

Conserved Domains (5) summary

PTZ00449
Location:1056 → 1332

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1342 → 1433

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522269.3 → XP_006522332.1 target of Nesh-SH3 isoform X22

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1317 → 1408

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522273.2 → XP_006522336.1 target of Nesh-SH3 isoform X28

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1264 → 1355

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522259.2 → XP_006522322.1 target of Nesh-SH3 isoform X9

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1377 → 1468

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522266.3 → XP_006522329.1 target of Nesh-SH3 isoform X18

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 1072

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1353 → 1444

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522271.3 → XP_006522334.1 target of Nesh-SH3 isoform X26

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1292 → 1383

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522275.2 → XP_006522338.1 target of Nesh-SH3 isoform X29

Conserved Domains (5) summary

PTZ00449
Location:1019 → 1229

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1239 → 1330

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522264.2 → XP_006522327.1 target of Nesh-SH3 isoform X15

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 1053

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1358 → 1449

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522256.3 → XP_006522319.1 target of Nesh-SH3 isoform X7

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 916

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1381 → 1472

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_036159992.1 → XP_036015885.1 target of Nesh-SH3 isoform X16

Conserved Domains (4) summary

PHA03247
Location:507 → 1002

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1356 → 1447

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 195

fn3; Fibronectin type III domain
XM_006522255.4 → XP_006522318.1 target of Nesh-SH3 isoform X6

Conserved Domains (3) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 892

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1382 → 1473

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522265.2 → XP_006522328.1 target of Nesh-SH3 isoform X17

Conserved Domains (4) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 1027

PHA03247; large tegument protein UL36; Provisional

PRK11633
Location:451 → 539

PRK11633; cell division protein DedD; Provisional

cd00063
Location:1354 → 1445

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522262.2 → XP_006522325.1 target of Nesh-SH3 isoform X13

Conserved Domains (3) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:456 → 1059

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1364 → 1455

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522270.2 → XP_006522333.1 target of Nesh-SH3 isoform X23

Conserved Domains (3) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 966

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1316 → 1407

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_036159988.1 → XP_036015881.1 target of Nesh-SH3 isoform X3

Conserved Domains (4) summary

PTZ00449
Location:509 → 782

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

PHA03247
Location:545 → 1203

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1398 → 1489

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 195

fn3; Fibronectin type III domain
XM_036159991.1 → XP_036015884.1 target of Nesh-SH3 isoform X14

Conserved Domains (3) summary

PHA03247
Location:456 → 1055

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1360 → 1451

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 195

fn3; Fibronectin type III domain
XM_036159990.1 → XP_036015883.1 target of Nesh-SH3 isoform X11

Conserved Domains (3) summary

PHA03247
Location:507 → 889

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1375 → 1466

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 195

fn3; Fibronectin type III domain
XM_006522268.2 → XP_006522331.1 target of Nesh-SH3 isoform X21

Conserved Domains (3) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:456 → 1032

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1337 → 1428

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522272.3 → XP_006522335.1 target of Nesh-SH3 isoform X27

Conserved Domains (3) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:507 → 1074

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1269 → 1360

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522252.2 → XP_006522315.1 target of Nesh-SH3 isoform X2

UniProtKB/TrEMBL

A0A338P6S8

Related

ENSMUSP00000156096.2, ENSMUST00000231781.2

Conserved Domains (4) summary

PTZ00449
Location:509 → 775

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:545 → 1206

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1401 → 1492

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_017317038.2 → XP_017172527.1 target of Nesh-SH3 isoform X19

Conserved Domains (3) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:456 → 1058

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1347 → 1438

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_036159994.1 → XP_036015887.1 target of Nesh-SH3 isoform X25

Conserved Domains (3) summary

PHA03247
Location:507 → 1031

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1302 → 1393

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 195

fn3; Fibronectin type III domain
XM_036159989.1 → XP_036015882.1 target of Nesh-SH3 isoform X4

Conserved Domains (4) summary

PTZ00449
Location:509 → 764

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

PHA03247
Location:456 → 1085

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1390 → 1481

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:116 → 195

fn3; Fibronectin type III domain
XM_006522258.2 → XP_006522321.1 target of Nesh-SH3 isoform X10

Conserved Domains (3) summary

smart00060
Location:114 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:482 → 891

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1377 → 1468

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522280.3 → XP_006522343.1 target of Nesh-SH3 isoform X30

Conserved Domains (2) summary

PHA03247
Location:491 → 884

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:938 → 1029

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522282.2 → XP_006522345.1 target of Nesh-SH3 isoform X31

UniProtKB/TrEMBL

Q59IW8

Conserved Domains (2) summary

PHA03247
Location:456 → 915

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:893 → 984

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522283.2 → XP_006522346.1 target of Nesh-SH3 isoform X32

UniProtKB/TrEMBL

Q59IW8

Conserved Domains (2) summary

PHA03247
Location:375 → 711

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:709 → 800

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522284.2 → XP_006522347.1 target of Nesh-SH3 isoform X33

UniProtKB/TrEMBL

B2RWZ0

Conserved Domains (2) summary

PHA03247
Location:350 → 686

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:684 → 775

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_006522285.2 → XP_006522348.1 target of Nesh-SH3 isoform X34

UniProtKB/TrEMBL

A0A338P6W9, B2RWZ0

Related

ENSMUSP00000156155.2, ENSMUST00000231832.2

Conserved Domains (2) summary

PHA03247
Location:317 → 650

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:648 → 739

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...