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Zhx3 zinc fingers and homeoboxes 3 [ Mus musculus (house mouse) ]

Gene ID: 320799, updated on 16-Oct-2021

Summary

Official Symbol
Zhx3provided by MGI
Official Full Name
zinc fingers and homeoboxes 3provided by MGI
Primary source
MGI:MGI:2444772
See related
Ensembl:ENSMUSG00000035877
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tix1; mKIAA0395; 1810059C13Rik; 4932418O04Rik; 9530010N21Rik
Expression
Ubiquitous expression in testis adult (RPKM 19.3), kidney adult (RPKM 7.4) and 25 other tissues See more
Orthologs
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Genomic context

See Zhx3 in Genome Data Viewer
Location:
2; 2 H2
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (160612367..160714910, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (160770447..160872990, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (160596183..160698726, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115489488 Neighboring gene topoisomerase (DNA) I Neighboring gene predicted gene, 54128 Neighboring gene phospholipase C, gamma 1 Neighboring gene predicted gene, 35129 Neighboring gene lipin 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Potential readthrough

Included gene: Plcg1

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell cortex ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc fingers and homeoboxes protein 3
Names
triple homeobox 1
triple homeobox protein 1
zinc finger and homeodomain protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177263.3NP_796237.2  zinc fingers and homeoboxes protein 3

    See identical proteins and their annotated locations for NP_796237.2

    Status: PROVISIONAL

    Source sequence(s)
    BC058111
    Consensus CDS
    CCDS16997.1
    UniProtKB/Swiss-Prot
    Q8C0Q2
    UniProtKB/TrEMBL
    Q3UPQ8
    Related
    ENSMUSP00000105086.2, ENSMUST00000109460.8
    Conserved Domains (4) summary
    smart00389
    Location:616661
    HOX; Homeodomain
    COG5576
    Location:495613
    COG5576; Homeodomain-containing transcription factor [Transcription]
    cd00086
    Location:495548
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam11569
    Location:845887
    Homez; Homeodomain leucine-zipper encoding, Homez

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    160612367..160714910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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