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CG9360 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32128, updated on 10-May-2024

Summary

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Official Symbol
CG9360provided by FlyBase
Primary source
FLYBASE:FBgn0030332
Locus tag
Dmel_CG9360
See related
AllianceGenome:FB:FBgn0030332
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9360; FOHSDR
Summary
Predicted to enable 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; 17-beta-ketosteroid reductase activity; and 3-keto sterol reductase activity. Is expressed in adult head; embryonic midgut chamber; and embryonic/larval midgut. Orthologous to human DHRS11 (dehydrogenase/reductase 11). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG9360 in Genome Data Viewer
Location:
10E2-10E2; 1-36 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11763474..11764590, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11657507..11658623, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene inaF-D Neighboring gene inaF-B Neighboring gene inaF-C Neighboring gene inaF-A Neighboring gene pseudo Neighboring gene miniature Neighboring gene dusky Neighboring gene antisense RNA:CR44962 Neighboring gene karl

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An RDH-Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase. Zhao X, et al. EMBO Rep, 2022 Feb 3. PMID 35132760, Free PMC Article
  2. Effect of Low Doses (5-40 cGy) of Gamma-irradiation on Lifespan and Stress-related Genes Expression Profile in Drosophila melanogaster. Zhikrevetskaya S, et al. PLoS One, 2015. PMID 26248317, Free PMC Article
  3. Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila. Landry CR, et al. Genetics, 2005 Dec. PMID 16143608, Free PMC Article
  4. Evolutionary changes in cis and trans gene regulation. Wittkopp PJ, et al. Nature, 2004 Jul 1. PMID 15229602
  5. Cyclin-dependent kinase 8 module expression profiling reveals requirement of mediator subunits 12 and 13 for transcription of Serpent-dependent innate immunity genes in Drosophila. Kuuluvainen E, et al. J Biol Chem, 2014 Jun 6. PMID 24778181, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 17-beta-hydroxysteroid dehydrogenase (NADP+) activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables 17-beta-ketosteroid reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables 3-keto sterol reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables estradiol 17-beta-dehydrogenase [NAD(P)] activity ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9360-PA
NP_572746.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11763474..11764590 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132518.3 → NP_572746.1  uncharacterized protein Dmel_CG9360 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572746.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VYU9
    Related
    FBpp0073450
    Conserved Domains (2) summary
    COG4221
    Location:1 → 250
    YdfG; NADP-dependent 3-hydroxy acid dehydrogenase YdfG [Energy production and conversion]
    cl21454
    Location:1 → 246
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VYU9 Q9VYU9

Gene LinkOut

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