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gja13.1 gap junction protein alpha 13.1 [ Danio rerio (zebrafish) ]

Gene ID: 322617, updated on 27-Mar-2024

Summary

Official Symbol
gja13.1provided by ZNC
Official Full Name
gap junction protein alpha 13.1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1337
See related
Ensembl:ENSDARG00000041787 AllianceGenome:ZFIN:ZDB-GENE-030131-1337
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
gjab; cx20b; cx32.3; gja13.2; zgc:63997; wu:fb67g08
Summary
Predicted to enable gap junction channel activity. Predicted to be involved in cell-cell signaling. Predicted to act upstream of or within cell communication. Predicted to be located in gap junction and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of connexin complex. Human ortholog(s) of this gene implicated in coronary artery disease and myocardial infarction. Orthologous to human GJA4 (gap junction protein alpha 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 20
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (40753517..40755614, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (40856407..40858504, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene gap junction protein alpha 12.2 Neighboring gene gap junction protein, alpha 12.1 Neighboring gene gap junction protein, alpha 11 Neighboring gene hydroxysteroid dehydrogenase like 1 Neighboring gene TBC1 domain family, member 32

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell communication IEA
Inferred from Electronic Annotation
more info
 
involved_in cell-cell signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
 
part_of connexin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of connexin complex IEA
Inferred from Electronic Annotation
more info
 
located_in gap junction IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
connexin 32.3
Names
gap junction protein alpha 13.2
gap junction protein, alpha b
novel connexin family protein (zgc:63997)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199612.2NP_955906.1  connexin 32.3

    See identical proteins and their annotated locations for NP_955906.1

    Status: VALIDATED

    Source sequence(s)
    EH504952, EH510943
    UniProtKB/TrEMBL
    A0A2R8QN02, F6NT52, Q7T2D7
    Related
    ENSDARP00000061246.4, ENSDART00000061247.6
    Conserved Domains (3) summary
    smart00037
    Location:4376
    CNX; Connexin homologues
    smart01089
    Location:151217
    Connexin_CCC; Gap junction channel protein cysteine-rich domain
    pfam00029
    Location:3219
    Connexin; Connexin

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    40753517..40755614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)