U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG31793 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 326161, updated on 4-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
CG31793provided by FlyBase
Primary source
FLYBASE:FBgn0051793
Locus tag
Dmel_CG31793
See related
AllianceGenome:FB:FBgn0051793
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10441; CG17338; DmCG31793; Dmel\CG31793
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. Predicted to be active in membrane. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; allergic bronchopulmonary aspergillosis; bronchial disease (multiple); congenital bilateral absence of vas deferens (multiple); and lung disease (multiple). Orthologous to several human genes including ABCC4 (ATP binding cassette subfamily C member 4). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
37B9-37B9; 2-54 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19003367..19008234)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19003367..19008234)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Ribosomal protein L30 Neighboring gene robl37BC

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. Mayer F, et al. J Neurosci, 2009 Mar 18. PMID 19295159, Free PMC Article
  2. Identification and characterization of a heme exporter from the MRP family in Drosophila melanogaster. Wang Z, et al. BMC Biol, 2022 Jun 2. PMID 35655259, Free PMC Article
  3. Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. Denecke S, et al. Proc Biol Sci, 2022 May 25. PMID 35582794, Free PMC Article
  4. TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels. Ren Q, et al. Nucleic Acids Res, 2007 Jan. PMID 17135193, Free PMC Article
  5. ATP-Binding Cassette (ABC) Transporter Genes Involved in Pyrethroid Resistance in the Malaria Vector Anopheles sinensis: Genome-Wide Identification, Characteristics, Phylogenetics, and Expression Profile. He Q, et al. Int J Mol Sci, 2019 Mar 20. PMID 30897799, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG31793-PA
CG31793-PC
NP_001286082.1
NP_609930.4

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    19003367..19008234
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299153.1 → NP_001286082.1  uncharacterized protein Dmel_CG31793, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286082.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q960T8, X2JAE9
    Conserved Domains (4) summary
    cd03244
    Location:953 → 1174
    ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
    cd03250
    Location:340 → 538
    ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
    TIGR01271
    Location:13 → 1179
    CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
    cl00549
    Location:18 → 270
    ABC_membrane; ABC transporter transmembrane region

  2. NM_136086.6 → NP_609930.4  uncharacterized protein Dmel_CG31793, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609930.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MT77, Q960T8
    Related
    FBpp0080682
    Conserved Domains (4) summary
    cd03244
    Location:1047 → 1268
    ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
    cd03250
    Location:434 → 632
    ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
    TIGR01271
    Location:1 → 1273
    CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
    cl00549
    Location:112 → 364
    ABC_membrane; ABC transporter transmembrane region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MT77 Q8MT77
Q960T8 Q960T8
X2JAE9 X2JAE9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous