SdhBL Succinate dehydrogenase, subunit B (iron-sulfur)-like [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: SdhBLprovided by FlyBase
Official Full Name: Succinate dehydrogenase, subunit B (iron-sulfur)-likeprovided by FlyBase
Primary source: FLYBASE:FBgn0030975
Locus tag: Dmel_CG7349
See related: AllianceGenome:FB:FBgn0030975
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG7349; DHSB; Dmel\CG7349
Summary: Predicted to enable succinate dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone. Predicted to be active in mitochondrial membrane. Is expressed in adult head; organism; and spermatozoon. Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; gastrointestinal stromal tumor; mitochondrial complex II deficiency; paraganglioma; and pheochromocytoma. Orthologous to human SDHB (succinate dehydrogenase complex iron sulfur subunit B). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (18894446..18896581)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (18788479..18790614)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 2 iron, 2 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables electron transfer activity	IEA Inferred from Electronic Annotation more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables succinate dehydrogenase (quinone) activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in aerobic respiration	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial electron transport, succinate to ubiquinone	ISS Inferred from Sequence or Structural Similarity more info
involved_in respiratory electron transport chain	IBA Inferred from Biological aspect of Ancestor more info
involved_in tricarboxylic acid cycle	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrial membrane	IBA Inferred from Biological aspect of Ancestor more info

Names: CG7349-PA; CG7349-PC; SdhBL-PA; SdhBL-PC; ferredoxin; succinate dehydrogenase Iron-sulfur protein; succinate dehydrogenase [ubiquinone] iron-sulfur protein

NP_001285420.1

NP_573340.1

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The following sections contain reference sequences that belong to a specific genome build. Explain