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Dgkk diacylglycerol kinase kappa [ Mus musculus (house mouse) ]

Gene ID: 331374, updated on 23-Jun-2021

Summary

Official Symbol
Dgkkprovided by MGI
Official Full Name
diacylglycerol kinase kappaprovided by MGI
Primary source
MGI:MGI:3580254
See related
Ensembl:ENSMUSG00000062393
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm360
Annotation information
Note: This gene aligns across a gap in the GRCm38 reference genome assembly, and therefore, the 5' end of this gene was annotated on NT_039699.8 and the 3' end was annotated on NT_039700.8 in NCBI's Mus Musculus Annotation Release 105. [15 Jun 2015]
Expression
Biased expression in CNS E18 (RPKM 1.2), CNS E14 (RPKM 0.6) and 9 other tissues See more
Orthologs
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Genomic context

See Dgkk in Genome Data Viewer
Location:
X; X A1.1
Exon count:
28
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (6691103..6814602)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (6779306..6948363)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (6356432..6356762) , (6450607..6525489)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein 15 Neighboring gene RIKEN cDNA 5430428K19 gene Neighboring gene shroom family member 4 Neighboring gene cyclin B3 Neighboring gene A kinase (PRKA) anchor protein 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables diacylglycerol kinase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in intracellular signal transduction ISO
Inferred from Sequence Orthology
more info
 
involved_in response to oxidative stress ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
diacylglycerol kinase kappa
NP_808582.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177914.3NP_808582.3  diacylglycerol kinase kappa

    Status: VALIDATED

    Source sequence(s)
    AL671962, AW121906, BC075627
    Consensus CDS
    CCDS85745.1
    UniProtKB/TrEMBL
    E9Q7N4, Q6DIC8
    Related
    ENSMUSP00000123079.3, ENSMUST00000145302.3
    Conserved Domains (5) summary
    smart00046
    Location:336458
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:170219
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd13274
    Location:60154
    PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain
    pfam00169
    Location:59147
    PH; PH domain
    cl02440
    Location:703860
    DAGK_acc; Diacylglycerol kinase accessory domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    6691103..6814602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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