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Gr21a Gustatory receptor 21a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33251, updated on 10-May-2024

Summary

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Official Symbol
Gr21aprovided by FlyBase
Official Full Name
Gustatory receptor 21aprovided by FlyBase
Primary source
FLYBASE:FBgn0041250
Locus tag
Dmel_CG13948
See related
AllianceGenome:FB:FBgn0041250
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
(GR) 21a; 21D.1; CG13948; Dmel\CG13948; DmGr21a; gr21a; GR21a; GR21D.1; Gr21D1; GR21D1
Summary
Predicted to enable olfactory receptor activity. Involved in detection of carbon dioxide and response to carbon dioxide. Located in dendrite and neuronal cell body. Is expressed in chemosensory neurons; head segment; and larval gnathal ganglion. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Gr21a in Genome Data Viewer
Location:
21E2-21E2; 2-1.5 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (780482..782885)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (780482..782885)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Protein kinase, cGMP-dependent at 21D Neighboring gene long non-coding RNA:CR45259

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Contributions of the Conserved Insect Carbon Dioxide Receptor Subunits to Odor Detection. Kumar A, et al. Cell Rep, 2020 Apr 14. PMID 32294446, Free PMC Article
  2. Carbon dioxide and fruit odor transduction in Drosophila olfactory neurons. What controls their dynamic properties? French AS, et al. PLoS One, 2014. PMID 24466044, Free PMC Article
  3. Modification of CO2 avoidance behaviour in Drosophila by inhibitory odorants. Turner SL, et al. Nature, 2009 Sep 10. PMID 19710651
  4. Evolution of the gene lineage encoding the carbon dioxide receptor in insects. Robertson HM, et al. J Insect Sci, 2009. PMID 19613462, Free PMC Article
  5. The olfactory sensory map in Drosophila. Laissue PP, et al. Adv Exp Med Biol, 2008. PMID 18683641

See all (115) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables taste receptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of carbon dioxide IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in response to carbon dioxide IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sensory perception of taste IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of taste NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
gustatory receptor 21a
Names
CG13948-PA
CG13948-PB
Gr21a-PA
Gr21a-PB
gustatory receptor 21D.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    780482..782885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078724.6 → NP_523448.2  gustatory receptor 21a, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523448.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A1C3L0, Q1WW99, Q9VPT1
    UniProtKB/TrEMBL
    M9PAZ2
    Related
    FBpp0077671
    Conserved Domains (1) summary
    pfam08395
    Location:75 → 438
    7tm_7; 7tm Chemosensory receptor

  2. NM_001272912.1 → NP_001259841.1  gustatory receptor 21a, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259841.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A1C3L0, Q1WW99, Q9VPT1
    UniProtKB/TrEMBL
    M9PAZ2
    Conserved Domains (1) summary
    pfam08395
    Location:75 → 438
    7tm_7; 7tm Chemosensory receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PAZ2 M9PAZ2
Q9VPT1.3 Q9VPT1

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